过氧化丁酮
过氧化丁酮用途
用作不饱和聚酯树脂的常温固化剂、有机合成的引发剂、漂白剂、杀菌剂
【用途二】
在聚酯及丙烯酸系聚合物生产中用作催化剂，是最安全的过氧化物。还广泛用于强化聚酯玻璃纤维生产作硬化剂。
【用途三】
不饱和聚酯树脂常温固化引发剂。
过氧化丁酮名称
[ CAS 号 ]:
1338-23-4
[ 中文名 ]:
2-过氧化丁酮
[ 英文名 ]:
Dioxydi-2,2-butanediyl dihydroperoxide
[中文别名 ]:
[英文别名 ]:
- MFCD00042641
- dioxydibutane-2,2-diyl dihydroperoxide
- kayamekm
- ketonox
- Hydroperoxide, (dioxybis(1-methylpropylidene))bis-
- mepox
- mekp
- Hi-Point 90 (in DMP)
- kayameka
- Dioxydi-2,2-butanediyl dihydroperoxide
过氧化丁酮物理化学性质
[ 密度 ]:
1.2±0.1 g/cm3
[ 沸点 ]:
304.9±27.0 °C at 760 mmHg
[ 熔点 ]:
110°C
[ 分子式 ]:
C8H18O6
[ 分子量 ]:
210.225
[ 闪点 ]:
138.2±23.7 °C
[ 精确质量 ]:
210.110336
[ PSA ]:
77.38000
[ LogP ]:
3.65
[ 外观性状 ]:
透明液体
[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C
[ 折射率 ]:
1.454
[ 储存条件 ]:
库房通风低温,轻装轻卸,与有机物、还原剂、硫、磷易燃物,食品原料分开存放
[ 水溶解性 ]:
0.1-0.5 g/100 mL at 22 ºC
过氧化丁酮MSDS
过氧化丁酮毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EL9450000
- CHEMICAL NAME :
- 2-Butanone, peroxide
- CAS REGISTRY NUMBER :
- 1338-23-4
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 31
- MOLECULAR FORMULA :
- C8-H16-O4
- MOLECULAR WEIGHT :
- 176.24
- WISWESSER LINE NOTATION :
- 1V2OO2V1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 480 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - changes in structure or function of esophagus Gastrointestinal - nausea or vomiting Gastrointestinal - other changes
- REFERENCE :
- NCPBBY National Clearinghouse for Poison Control Centers, Bulletin. (U.S. Department of Health, Education, and Welfare, Washington, DC) Volume(issue)/page/year: Jan/Feb,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 484 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 ppm/4H
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 65 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - ataxia
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 470 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 165,201,1957
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 170 ppm/4H
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2033 mg/kg/7W-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 273 mg/kg/7W-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,205,1958 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 282 mg/kg
- REFERENCE :
- RARSAM Radiation Research, Supplement. (New York, NY) No.1-7, 1959-67. Discontinued. Volume(issue)/page/year: 3,193,1963 *** REVIEWS *** ACGIH TLV-CL 1.5 mg/m3 (0.2 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.2 ppm (1.5 mg/m3) JAN 1993 OEL-BELGIUM:STEL 0.2 ppm (1.5 mg/m3) JAN 1993 OEL-DENMARK:STEL 1 mg/m3 JAN 1993 OEL-FINLAND:STEL 0.2 ppm (1.5 mg/m3);Skin JAN 1993 OEL-FRANCE:STEL 0.2 ppm (1.5 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 0.2 ppm (1.5 mg/m3) JAN 1993 OEL-SWEDEN:STEL 0.2 ppm (1.5 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 0.2 ppm (1.5 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 0.2 ppm (1.5 mg/m3);STEL 0.2 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO METHYL ETHYL KETONE PEROXIDE-air:CL 0.2 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80105 No. of Facilities: 2226 (estimated) No. of Industries: 29 No. of Occupations: 31 No. of Employees: 20053 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80105 No. of Facilities: 1879 (estimated) No. of Industries: 23 No. of Occupations: 31 No. of Employees: 25827 (estimated) No. of Female Employees: 6514 (estimated)
过氧化丁酮安全信息
[ 符号 ]:
GHS02, GHS05
[ 信号词 ]:
Danger
[ 危害声明 ]:
H242-H314
[ 警示性声明 ]:
P220-P280-P305 + P351 + P338-P310-P410-P411 + P235
[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
O:Oxidizingagent;C:Corrosive;
[ 风险声明 (欧洲) ]:
R7;R22;R34
[ 安全声明 (欧洲) ]:
S17-S26-S36/37/39-S45-S14-S53-S3/7-S47-S7
[ 危险品运输编码 ]:
UN 3105 5.2
[ WGK德国 ]:
1
[ 包装等级 ]:
II
[ 危险类别 ]:
5.2
[ 海关编码 ]:
2909600000
过氧化丁酮制备
1.在硫酸存在下，由甲乙酮与过氧化氢（双氧水）反应制取。经氧化、中和、分离、脱水、静置、过滤，最后加入增溶剂而得成品
2.由双氧水与丁酮制备MEKP是在酸性介质中进行的，反应按下列方式进行：
将双氧水和丁酮加入反应釜中[30%的过氧化氢与丁酮的摩尔比为(1.6～1.9)∶1]加入滴加量为H2O2质量25%的液体催化剂（磷酸，用量以总质量计为20%～30%）；边滴边搅拌，并控制温度在25℃左右，置入H2O2加料贮槽中备用。然后按同一摩尔比配好丁酮后置入丁酮加料贮槽中。在合成反应器中置入稀释剂二丁酯启动反应器搅拌器，同时向反应器中加入H2O和丁酮，加料时间需1h左右，反应温度为25℃以下，加料完毕后继续反应一段时间。反应后的产物经液液分离后，废催化剂排放，同时加入内稳定剂和碳酸钠，产品pH值调至5。再加干燥剂干燥至无色透明，过滤除去固体组分，常温下真空脱除残留的水分，即得合格产品。产品的活性氧可达11%，产品收率>95%。
3.制法：
于1L烧杯中加入丁酮（2）217g（3.0mol），冰水浴冷却下慢慢滴加30%的双氧水330g（3.0mol），控制反应液温度在20～25℃，加完后反应液为清亮溶液。于另一1L烧杯中加入30mL（10%）的盐酸，冰浴冷却，搅拌下慢慢加入上面的溶液，反应放热，注意控制加入速度，以使反应液温度在20～25℃之间。加完后再搅拌1h。加入100g氯化铵或硫酸铵，搅拌溶解，盐析出产品。分出有机层，无水硫酸钠干燥，过滤，得产品（1）240g，收率82%。
过氧化丁酮海关
[ 海关编码 ]: 2909600000
[ 中文概述 ]:
2909600000 过氧化醇、过氧化醚、过氧化酮及其卤化、磺化、硝化、亚硝化衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2909600000 alcohol peroxides, ether peroxides, ketone peroxides and their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
过氧化丁酮文献
J. Toxicol. Clin. Exp. 12(4-5) , 205-6, (1992)
Effect of dietary vitamin E on methyl ethyl ketone peroxide damage to microsomal cytochrome P-450 peroxidase.
Chem. Biol. Interact. 55(3) , 317-26, (1985)
The effect of dietary vitamin E on in vivo and in vitro damage by methyl ethyl ketone peroxide (MEKP) to cytochrome P-450 and its associated enzymatic activity was studied. In vivo, MEKP damaged micro...
Contact sensitivity to methyl ethyl ketone peroxide in a paint sprayer.Contact Dermatitis 26(1) , 52-3, (1992)
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：2-过氧化丁酮
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥308.0/500ml
￥108.0/100ml
联系人：刘佳
产品详情：2-过氧化丁酮
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥需询单/1mg
￥需询单/1mg
￥需询单/1mg
￥需询单/1mg
联系人：阿拉丁
产品详情：2-过氧化丁酮
公司名：中山市迪欣化工有限公司
区域：中山市三角镇
价格：
￥30.0/200kg
联系人：董生
产品详情：过氧化丁酮
查看所有供应商请点击：
相关化合物
【过氧化丁酮】化源网提供过氧化丁酮CAS号1338-23-4，过氧化丁酮MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询过氧化丁酮上化源网，专业又轻松。>>电脑版：过氧化丁酮
标题：过氧化丁酮_MSDS_用途_密度_过氧化丁酮CAS号【1338-23-4】_化源网 地址：https://m.chemsrc.com/mip/cas/1338-23-4_248359.html