5-((2-(二乙基氨基)乙基)氨基)-8-羟基-6H-咪唑并[4,5,1-de]吖啶-6-酮
用途
名称
[ CAS 号 ]:
138154-39-9
[ 中文名 ]:
5-((2-(二乙基氨基)乙基)氨基)-8-羟基-6H-咪唑并[4,5,1-de]吖啶-6-酮
[ 英文名 ]:
C-1311
[英文别名 ]:
- C 1311
- XLS-002
物理化学性质
[ 密度 ]:
1.32g/cm3
[ 沸点 ]:
605.8ºC at 760mmHg
[ 分子式 ]:
C20H22N4O2
[ 分子量 ]:
350.41400
[ 闪点 ]:
320.2ºC
[ 精确质量 ]:
350.17400
[ PSA ]:
69.87000
[ LogP ]:
2.97100
[ 蒸汽压 ]:
2.86E-15mmHg at 25°C
[ 折射率 ]:
1.68
安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302
[ 危险品运输编码 ]:
NONH for all modes of transport
合成路线
上下游产品
上游产品
下游产品
文献
J. Pharmacol. Exp. Ther. 346(3) , 393-405, (2013)
Imidazoacridinone 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor inhibitor of topoisomerase II and FMS-like tyrosine kinase 3 receptor. In this study, we describe the uni...
Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use.Drug Metab. Dispos. 41(2) , 414-21, (2013)
The acridinone derivates 5-dimethylaminopropylamino-8-hydroxytriazoloacridinone (C-1305) and 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) are promising antitumor agents with high activ...
Development and validation of an LC-UV method for the quantification and purity determination of the novel anticancer agent C1311 and its pharmaceutical dosage form.J. Pharm. Biomed. Anal. 39(1-2) , 46-53, (2005)
C1311 (5-[[2-(diethylamino)ethyl]amino]-8-hydroxyimidazo [4,5,1-de]-acridin-6-one-dihydrochloride trihydrate) is the lead compound from the group of imidazoacridinones, a novel group of rationally des...
推荐生产厂家/供应商:
热门化合物
CAS号[138154-39-9]化源网提供[5-((2-(二乙基氨基)乙基)氨基)-8-羟基-6H-咪唑并[4,5,1-de]吖啶-6-酮]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版:5-((2-(二乙基氨基)乙基)氨基)-8-羟基-6H-咪唑并[4,5,1-de]吖啶-6-酮
标题:138154-39-9_CAS号:138154-39-9_5-((2-(二乙基氨基)乙基)氨基)-8-羟基-6H-咪唑并[4,5,1-de]吖啶-6-酮 - 化源网 地址:https://m.chemsrc.com/mip/cas/138154-39-9_339.html