富马酸亚铁
富马酸亚铁用途
富马酸亚铁名称
[ CAS 号 ]:
141-01-5
[ 中文名 ]:
富马酸亚铁
[ 英文名 ]:
Iron(II) fumarate
[中文别名 ]:
[英文别名 ]:
- firon
- fumafer
- Iron(II) fumarate
- [But-2-enedioato(2-)-κO,O]iron
- feostat
- Fumaric acid, iron salt
- ircon
- Iron, [2-butenedioato(2-)-κO,κO]-
- galfer
- EINECS 205-447-7
富马酸亚铁生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
富马酸亚铁物理化学性质
[ 密度 ]:
2.435
[ 熔点 ]:
>280°C
[ 分子式 ]:
C4H2FeO4
[ 分子量 ]:
169.901
[ 精确质量 ]:
169.930252
[ PSA ]:
52.60000
[ 外观性状 ]:
红色至棕色粉末
[ 储存条件 ]:
库房低温,通风,干燥
[ 稳定性 ]:
Stability
富马酸亚铁毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LT1950000
- CAS REGISTRY NUMBER :
- 141-01-5
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C4-H2-O4.Fe
- MOLECULAR WEIGHT :
- 169.91
- WISWESSER LINE NOTATION :
- OV1U1VO &-FE-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - nausea or vomiting
- REFERENCE :
- HUTODJ Human Toxicology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants., RG 21 2XS, UK) V.1- 1981- Volume(issue)/page/year: 7,281,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3850 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,683,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 185 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,683,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,683,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1570 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AJMSA9 American Journal of the Medical Sciences. (Slack Inc., 6900 Grove Rd., Thorofare, NJ 08086) New series: V.1- 1841- Volume(issue)/page/year: 241,296,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 480 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AJMSA9 American Journal of the Medical Sciences. (Slack Inc., 6900 Grove Rd., Thorofare, NJ 08086) New series: V.1- 1841- Volume(issue)/page/year: 241,296,1961 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1 mg(Fe)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,138,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 1 mg(Fe)/m3 JAN 1993 OEL-FINLAND:TWA 1 mg(Fe)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 1 mg(Fe)/m3 JAN 1993 OEL-SWITZERLAND:TWA 1 mg(Fe)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 1 mg(Fe)/m3;STEL 2 mg(Fe)/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80414 No. of Facilities: 129 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 9131 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80414 No. of Facilities: 429 (estimated) No. of Industries: 3 No. of Occupations: 18 No. of Employees: 3859 (estimated) No. of Female Employees: 1728 (estimated)
富马酸亚铁安全信息
[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ 风险声明 (欧洲) ]:
R36/37/38
[ 安全声明 (欧洲) ]:
S22-S36/37/39
[ 危险品运输编码 ]:
NONH for all modes of transport
[ RTECS号 ]:
LT1950000
[ 海关编码 ]:
2917190090
富马酸亚铁制备
1. 烯二酸钠用硫酸亚铁置换而得。将水加热至沸,搅拌下加入反丁烯二酸,分次加入碳酸钠到pH=6.5-6.7。充分搅拌后趁热过滤,得反丁烯二酸钠溶液。加入硫酸亚铁溶液,搅拌加热回流3-4h,冷却结晶,甩滤。滤饼用蒸馏水洗至硫酸根符合要求为止,干燥,得富马酸亚铁,收率83%。
2.由富马酸与铁屑反应而得。
3.将5g富马酸加入100mL沸水中,并用碳酸钠中和至PH6.5-6.7;过滤,在所得的富马酸二钠溶液中加入13g硫酸亚铁和100mL水的溶液,并加热搅拌回流(100℃)反应3-4h;最后冷却、结晶、过滤、洗涤、干燥得红棕色粉末富马酸亚铁6.2-6.6g,收率85%-90%。
4.将5g富马酸加入100mL沸水中,并用碳酸钠中和至Ph值6.5~6.7;过滤,在所得的富马酸二钠溶液中加入13g硫酸亚铁和100mL水的溶液,并加热搅拌回流(100℃)反应3~4h;最后冷却、结晶、过滤、洗涤、干燥得红棕色粉末富马酸亚铁6.2~6.6g,收率85%~90%。
C4H4O4+Na2CO3→C4H2O4Na2+H2O+CO2↑
FeSO4+Na2C4H2O4→Na2SO4+FeC4H2O4
富马酸亚铁海关
[ 海关编码 ]: 2917190090
[ 中文概述 ]:
2917190090 其他无环多元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分
[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
富马酸亚铁文献
Am. J. Clin. Nutr. 101(1) , 210-7, (2015)
Food fortification is one approach for addressing anemia, but information on program effectiveness is limited.We evaluated the impact of Costa Rica's fortification program on anemia in women aged 15-4...
Rapid recovery time of hemoglobin level in female regular blood donors with ferrous fumarate and high dose of ascorbic acid supplement.J. Med. Assoc. Thai. 96(2) , 165-71, (2013)
Iron deficiency anemia has occurred more frequently in female than male regular blood donors. Iron supplement is necessary for maintaining the hemoglobin level. A combination with ascorbic acid increa...
[Effect of iron supplementation on iron deficiency anemia of childbearing age women in Shanghai].Wei Sheng Yan Jiu 41(1) , 51-5, (2012)
To investigate the effect of iron supplementation on iron deficiency anemia of childbearing age women, and to find out the optimal amount of iron intake for maintaining their health.74 childbearing ag...
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推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐乾明
产品详情:延胡索酸亚铁
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥518.0/5g
¥608.0/10g
¥428.0/1g
¥988.0/100g
联系人:刘佳
产品详情:延胡索酸亚铁
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥53.0/25g
¥112.0/100g
¥411.0/500g
¥1564.0/2500g
联系人:夏言
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥92.9/100g
¥1516.9/3kg
¥43.9/25g
¥343.9/500g
联系人:阿拉丁
产品详情:富马酸亚铁
公司名:中山市迪欣化工有限公司
区域:中山市三角镇
价格:
¥26.0/1000kg
联系人:王洁
产品详情:富马酸亚铁
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相关化合物
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