N-烯丙去甲间唑新

[ 密度 ]:
1.055g/cm3

[ 沸点 ]:
373.6ºC at 760mmHg

[ 分子式 ]:
C₁₇H₂₃NO

[ 分子量 ]:
257.37100

[ 闪点 ]:
169.9ºC

[ 精确质量 ]:
257.17800

[ PSA ]:
23.47000

[ LogP ]:
3.04030

[ 外观性状 ]:
solid | white

[ 蒸汽压 ]:
4.11E-06mmHg at 25°C

[ 折射率 ]:
1.559

[ 水溶解性 ]:
H2O: soluble

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H312-H332

[ 警示性声明 ]:
P280

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells.

Exp. Eye Res. 107 , 21-31, (2013)

Sigma-1 receptors (σ-1rs) exert neuroprotective effects on retinal ganglion cells (RGCs) both in vivo and in vitro. This receptor has unique properties through its actions on several voltage-gated and...

The C-terminal amidated analogue of the substance P (SP) fragment SP(1-7) attenuates the expression of naloxone-precipitated withdrawal in morphine dependent rats.

Peptides 30 , 2418-2422, (2009)

We previously demonstrated that intracerebroventricular (i.c.v.) administration of the substance P (SP) aminoterminal fragment SP(1-7) attenuates the expression of morphine withdrawal in the male rat....

Antagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channels.

Am. J. Physiol. Cell Physiol. 300(2) , C328-37, (2011)

σ-Receptors are integral membrane proteins that have been implicated in a number of biological functions, many of which involve the modulation of ion channels. A wide range of synthetic ligands activa...

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