盐酸士的宁

Strychnine Hydrochloride is a neurotoxin that acts as an antagonist of glycine and acetylcholine receptors.

[ 沸点 ]:
559.9ºC at 760mmHg

[ 熔点 ]:
295 °C

[ 分子式 ]:
C₂₁H₂₃ClN₂O₂

[ 分子量 ]:
370.872

[ 闪点 ]:
292.4ºC

[ 精确质量 ]:
370.144806

[ PSA ]:
32.78000

[ LogP ]:
2.89740

[ 外观性状 ]:
白色至浅米色固体

[ 蒸汽压 ]:
1.44E-12mmHg at 25°C

[ 储存条件 ]:
Store at RT

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

WL2430000

CHEMICAL NAME :

Strychnine, monohydrochloride

CAS REGISTRY NUMBER :

1421-86-9

LAST UPDATED :

199106

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C21-H22-N2-O2.Cl-H

MOLECULAR WEIGHT :

370.91

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2730 ug/kg

TOXIC EFFECTS :

Behavioral - rigidity (including catalepsy)

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

650 ug/kg

TOXIC EFFECTS :

Behavioral - general anesthetic

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

460 ug/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - dyspnea

MUTATION DATA

TYPE OF TEST :

Gene conversion and mitotic recombination

TEST SYSTEM :

Bacteria - Salmonella typhimurium

DOSE/DURATION :

3 mmol/L

REFERENCE :

EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10,27,1987

[ 符号 ]:

GHS06, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H300-H330-H410

[ 警示性声明 ]:
P260-P264-P273-P284-P301 + P310-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T+: Very toxic;N: Dangerous for the environment;

[ 风险声明 (欧洲) ]:
R26/27/28

[ 安全声明 (欧洲) ]:
S22-S36/37/39-S45-S61-S60

[ 危险品运输编码 ]:
UN 1692 6.1/PG 1

[ WGK德国 ]:
3

[ RTECS号 ]:
WL2430000

[ 包装等级 ]:
I

[ 危险类别 ]:
6.1(a)

Parallel ON and OFF cone bipolar inputs establish spatially coextensive receptive field structure of blue-yellow ganglion cells in primate retina.

J. Mol. Endocrinol. 29 , 8372-87, (2009)

In the primate retina the small bistratified, "blue-yellow" color-opponent ganglion cell receives parallel ON-depolarizing and OFF-hyperpolarizing inputs from short (S)-wavelength sensitive and combin...

Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1β Release.

J. Immunol. 195 , 2325-34, (2015)

IL-1β is a potent proinflammatory cytokine of the innate immune system that is involved in host defense against infection. However, increased production of IL-1β plays a pathogenic role in various inf...

Inhibitory Interneurons That Express GFP in the PrP-GFP Mouse Spinal Cord Are Morphologically Heterogeneous, Innervated by Several Classes of Primary Afferent and Include Lamina I Projection Neurons among Their Postsynaptic Targets.

J. Neurosci. 35 , 7626-42, (2015)

The superficial dorsal horn of the spinal cord contains numerous inhibitory interneurons, which regulate the transmission of information perceived as touch, pain, or itch. Despite the importance of th...

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公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：盐酸士的宁

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥4119.9/100mg ￥926.9/10mg ￥1750.9/25mg ￥2647.9/50mg

联系人：阿拉丁

产品详情：盐酸士的宁

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