3-亚硝基苯酰胺

3-亚硝基苯酰胺用途

抗反转录病毒药。能够移去病毒粒子蛋白中反转录病毒型的锌，而具有抗反转录病毒的作用。

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3-亚硝基苯酰胺名称

[ CAS 号 ]:
144189-66-2

[ 中文名 ]:
3-亚硝基苯酰胺

[ 英文名 ]:
3-nitrosobenzamide

[英文别名 ]:

N8153_FLUKA
MFCD00214342
Nitrosobenzamide
Benzamide,3-nitroso

3-亚硝基苯酰胺物理化学性质

[ 密度 ]:
1.33g/cm3

[ 沸点 ]:
317.5ºC at 760mmHg

[ 分子式 ]:
C₇H₆N₂O₂

[ 分子量 ]:
150.13500

[ 闪点 ]:
145.8ºC

[ 精确质量 ]:
150.04300

[ PSA ]:
72.52000

[ LogP ]:
1.88370

[ 蒸汽压 ]:
0.000384mmHg at 25°C

[ 折射率 ]:
1.607

[ 储存条件 ]:
2-8°C

3-亚硝基苯酰胺安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H314

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 危害码 (欧洲) ]:
C: Corrosive;

[ 风险声明 (欧洲) ]:
35

[ 安全声明 (欧洲) ]:
26-36/37/39-45

[ 危险品运输编码 ]:
UN 1759 8/PG 2

[ WGK德国 ]:
1

[ 海关编码 ]:
2924299090

3-亚硝基苯酰胺制备

3-氨基苯甲酰胺的溶液用间氯过苯甲酸氧化，有机层置冷凝器中72h，缓慢析出黄色固体，即为3-亚硝基苯甲酰胺。

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3-亚硝基苯酰胺海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

3-亚硝基苯酰胺文献

The site of antiviral action of 3-nitrosobenzamide on the infectivity process of human immunodeficiency virus in human lymphocytes.

Proc. Natl. Acad. Sci. U. S. A. 90 , 9721, (1993)

The C-nitroso compound 3-nitrosobenzamide, which has been shown to remove zinc from the retroviral-type zinc finger of p7NC nucleocapsid proteins, inhibits acute infection of human immunodeficiency vi...

Inhibition of the replication of native and 3'-azido-2',3'-dideoxythymidine (AZT)-resistant simian immunodeficiency virus (SIV) by 3-nitrosobenzamide.

FEBS Lett. 326 , 140, (1993)

The 3-nitrosobenzamide (NOBA) drug abolishes SIV replication sharply at 20 microM concentration when CEM x 174 cells are preincubated for 1 h with the drug prior to viral infection. Treatment of CEM x...

Structure/function correlations among coupled binuclear copper proteins through spectroscopic and reactivity studies of NspF.

Proc. Natl. Acad. Sci. U. S. A. 109(27) , 10793-7, (2012)

The terminal step of 4-hydroxy-3-nitrosobenzamide biosynthesis in Streptomyces murayamaensis is performed by NspF, a mono-oxygenase that converts o-aminophenols to the corresponding nitroso product (h...

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