4'-氯地西泮
4'-氯地西泮用途
4'-氯地西泮名称
[ CAS 号 ]:
14439-61-3
[ 中文名 ]:
4'-氯地西泮
[ 英文名 ]:
4'-Chlorodiazepam
[英文别名 ]:
- Chlorodiazepam
- 4'-Chlorodiazepam
- Ro-5-4864
4'-氯地西泮物理化学性质
[ 密度 ]:
1.35g/cm3
[ 沸点 ]:
517.1ºC at 760mmHg
[ 熔点 ]:
160-163ºC
[ 分子式 ]:
C16H12Cl2N2O
[ 分子量 ]:
319.18500
[ 闪点 ]:
266.6ºC
[ 精确质量 ]:
318.03300
[ PSA ]:
32.67000
[ LogP ]:
3.30780
[ 蒸汽压 ]:
8.43E-11mmHg at 25°C
[ 折射率 ]:
1.647
[ 储存条件 ]:
2-8℃,干燥,密闭
4'-氯地西泮毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DF0500000
- CHEMICAL NAME :
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(p-chlorophenyl)-1,3-dihydro-1-methyl-
- CAS REGISTRY NUMBER :
- 14439-61-3
- BEILSTEIN REFERENCE NO. :
- 0685202
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C16-H12-Cl2-N2-O
- MOLECULAR WEIGHT :
- 319.20
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - rat Cells - not otherwise specified
- DOSE/DURATION :
- 10 nmol/L
- REFERENCE :
- CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 49,115,1990
4'-氯地西泮安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xn: Harmful;
[ 风险声明 (欧洲) ]:
22
[ 危险品运输编码 ]:
UN 2811
[ RTECS号 ]:
DF0500000
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1(b)
[ 海关编码 ]:
2933990090
4'-氯地西泮合成路线
4'-氯地西泮上下游产品
4'-氯地西泮上游产品
4'-氯地西泮下游产品
4'-氯地西泮海关
[ 海关编码 ]: 2933990090
[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
4'-氯地西泮文献
J. Med. Chem. 49 , 5845-8, (2006)
Cultured rat astrocytes and C6 rat glioma were used as a differential screen for a variety of 1,2,3,4-tetrahydroisoquinoline (THI) derivatives. Compound 1 [1-(biphenyl-4-ylmethyl)-1,2,3,4-tetrahydrois...
Investigation into mechanisms mediating the inhibitory effect of 1,4-benzodiazepines on mast cells by gene expression profiling.Life Sci. 92(6-7) , 345-51, (2013)
This study aims to identify by a molecular genetic approach potential targets in mast cells at which 1,4-benzodiazepines may cause their inhibitory effect on mast cell activity.Gene expression analyse...
Translocator protein (18 kDa) as a pharmacological target in adipocytes to regulate glucose homeostasis.Biochem. Pharmacol. 97 , 99-110, (2015)
As a major regulator in obesity and its associated metabolic complications, the proper functioning of adipocytes is crucial for health maintenance, thus serving as an important target for the developm...
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推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐乾明
产品详情:4'-Chlorodiazepam
公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
价格:
¥需询单/1g
联系人:赖经理
产品详情:Ro5-4864
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相关化合物
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