7-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

名称

[ CAS 号 ]:
144485-81-4

[ 英文名 ]:
7-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

物理化学性质

[ 密度 ]:
1.4g/cm3

[ 沸点 ]:
557.6ºC at 760mmHg

[ 分子式 ]:
C18H12ClN3O2

[ 分子量 ]:
337.76000

[ 闪点 ]:
291ºC

[ 精确质量 ]:
337.06200

[ PSA ]:
60.92000

[ LogP ]:
4.00250

[ 蒸汽压 ]:
1.81E-12mmHg at 25°C

[ 折射率 ]:
1.69

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA2807010
CHEMICAL NAME :
4(3H)-Quinazolinone, 7-chloro-3-(3-methyl-5-isoxazolyl)-2-phenyl-
CAS REGISTRY NUMBER :
144485-81-4
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H12-Cl-N3-O2
MOLECULAR WEIGHT :
337.78

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992
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CAS号[144485-81-4]化源网提供[7-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版：7-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

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