6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

名称

[ CAS 号 ]:
144485-85-8

[ 英文名 ]:
6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

物理化学性质

[ 密度 ]:
1.4g/cm3

[ 沸点 ]:
557.6ºC at 760mmHg

[ 分子式 ]:
C₁₈H₁₂ClN₃O₂

[ 分子量 ]:
337.76000

[ 闪点 ]:
291ºC

[ 精确质量 ]:
337.06200

[ PSA ]:
60.92000

[ LogP ]:
4.00250

[ 蒸汽压 ]:
1.81E-12mmHg at 25°C

[ 折射率 ]:
1.69

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA2807000

CHEMICAL NAME :: 4(3H)-Quinazolinone, 6-chloro-3-(3-methyl-5-isoxazolyl)-2-phenyl-

CAS REGISTRY NUMBER :: 144485-85-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C18-H12-Cl-N3-O2

MOLECULAR WEIGHT :: 337.78

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one

名称

物理化学性质

毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

合成路线

详细合成路线

上下游产品

上游产品

下游产品

推荐生产厂家/供应商：

相关化合物