邻苯二甲酰肼

【用途一】
用作医药双肼酞嗪的中间体。

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
523.5ºC at 760 mmHg

[ 熔点 ]:
>300 °C(lit.)

[ 分子式 ]:
C₈H₆N₂O₂

[ 分子量 ]:
162.145

[ 闪点 ]:
270.4ºC

[ 精确质量 ]:
162.042923

[ PSA ]:
65.72000

[ LogP ]:
0.57

[ 外观性状 ]:
白色粉末和块

[ 蒸汽压 ]:
1.41E-11mmHg at 25°C

[ 折射率 ]:
1.587

[ 储存条件 ]:
室温

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

TH8890080

CHEMICAL NAME :

1,4-Phthalazinedione, 2,3-dihydro-

CAS REGISTRY NUMBER :

1445-69-8

LAST UPDATED :

199509

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C8-H6-N2-O2

MOLECULAR WEIGHT :

162.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

700 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

ARPMAS Archiv der Pharmazie (Weinheim, Germany) (VCH Pub., Inc., 303 NW 12th Ave., Deerfield Beach, FL 33441) V.51-261, 1835-1923; V.305- 1972- Volume(issue)/page/year: 327,237,1994 ** REPRODUCTIVE DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

700 mg/kg

SEX/DURATION :

female 7 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :

ARPMAS Archiv der Pharmazie (Weinheim, Germany) (VCH Pub., Inc., 303 NW 12th Ave., Deerfield Beach, FL 33441) V.51-261, 1835-1923; V.305- 1972- Volume(issue)/page/year: 327,237,1994

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
TH8890080

[ 海关编码 ]:
2933990090

邻苯二甲酰肼上游产品

邻苯二甲酰肼下游产品

由苯酐与水合肼反应而得。将乙醇、水合肼、苯酐依次投入反应锅，搅拌，升温回流8h。蒸出乙醇至反应物成糊状。冷却至40℃，加适量水，甩滤，水洗至pH6.5，干燥得双酮酞嗪。

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Effects of 2,3-dihydrophthalazine-1,4-dione on Sprague Dawley rats lipid metabolism and serum lipoproteins.

Biomed. Biochim. Acta 47(4-5) , 423-33, (1988)

2,3-Dihydrophthalazine-1,4-dione effectively lowers serum levels of cholesterol and triglycerides in Sprague Dawley rats after two weeks, after which the cholesterol levels continued to decline. The m...

Anti-inflammatory activity of 2,3-dihydrophthalazine-1,4-diones in CF1 mice.

Int. J. Tissue React. 18(2-3) , 47-55, (1996)

2,3-Dihydrophthalazine-1,4-diones were observed to be potent anti-inflammatory agents as well as capable of protecting against endotoxin shock in mice at 8 mg/kg i.p. These agents blocked both locally...

The anti-neoplastic activity of 2,3-dihydrophthalazine-1,4-dione and N-butyl-2,3-dihydrophthalazine-1,4-dione in human and murine tumor cells.

Anticancer Drugs 3(1) , 55-62, (1992)

2,3-Dihydrophthalazine-1,4-dione derivatives demonstrated potent cytotoxicity against the growth of murine leukemia cells and human single cell suspension, i.e. Tmolt3 leukemia and HeLa-S3, as well as...

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公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

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公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥328.0/100g ￥118.0/25g

联系人：刘佳

产品详情：邻苯二甲酰肼

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥1128.9/3kg ￥82.9/100g ￥57.9/25g ￥328.9/500g

联系人：阿拉丁

产品详情：邻苯二甲酰肼

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公司名：上海创赛科技有限公司

区域：上海市嘉定区

价格：
￥61.0/25g ￥142.0/100g ￥475.0/500g ￥1798.0/2500g

联系人：夏言

产品详情：[Perfemiker]邻苯二甲酰肼,99%

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