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蜂毒肽

蜂毒肽用途

Mastoparan 17是一种十四肽。马斯托潘17是马斯托潘(HY-P0246)[1]的非活性类似物。

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蜂毒肽名称

[ CAS 号 ]:
145854-61-1

[ 中文名 ]:
蜂毒肽

[ 英文名 ]:
Mastoparan 17

[中文别名 ]:

蜂毒素

[英文别名 ]:

INLKAKAALAKKLL-NH2
MAS 17

蜂毒肽生物活性

[ 描述 ]:

Mastoparan 17是一种十四肽。马斯托潘17是马斯托潘(HY-P0246)[1]的非活性类似物。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

蜂毒肽物理化学性质

[ 分子式 ]:
C₇₀H₁₃₂N₂₀O₁₅

[ 分子量 ]:
1493.92000

[ 精确质量 ]:
1493.02000

[ PSA ]:
594.58000

[ LogP ]:
6.78670

[ 储存条件 ]:
-20°C

蜂毒肽MSDS

详细MSDS(安全技术说明书)

蜂毒肽安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3.0

蜂毒肽文献

Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity.

J. Biol. Chem. 265 , 14176, (1990)

Mastoparan (MP), a cationic, amphiphilic tetradecapeptide, stimulates guanine nucleotide exchange by GTP-binding regulatory proteins (G proteins) in a manner similar to that of G protein-coupled recep...

Exocytosis in chromaffin cells: evidence for a MgATP-independent step that requires a pertussis toxin-sensitive GTP-binding protein.

Biochem. J. 15 , 217-227, (1994)

We have previously described that mastoparan, an amphiphilic tetradecapeptide that activates heterotrimeric G-proteins, inhibits Ca(2+)-induced MgATP-dependent secretion from streptolysin-O-permeabili...

Evidence of heterotrimeric G-protein involvement in regulated exocytosis from permeabilized pancreatic acini.

Pancreas 10 , 374, (1995)

Constitutive membrane trafficking events are regulated by heterotrimeric G-proteins (G-proteins) in addition to their regulation by small GTP-binding proteins (smgs). Here, we used streptolysin O-perm...

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蜂毒肽