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4-脱氧吡哆醇盐酸盐

4-脱氧吡哆醇盐酸盐用途

4-脱氧吡啶(盐酸盐)是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

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4-脱氧吡哆醇盐酸盐名称

[ CAS 号 ]:
148-51-6

[ 中文名 ]:
4-脱氧吡哆醇盐酸盐

[ 英文名 ]:
4-Deoxy pyridoxine hydrochloride

[中文别名 ]:

[英文别名 ]:

MFCD00051296
4-Deoxy Pyridoxine Hydrochloride
EINECS 205-714-8
4-Deoxypyridoxine Hydrochloride

4-脱氧吡哆醇盐酸盐生物活性

[ 描述 ]:

4-脱氧吡啶(盐酸盐)是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

4-脱氧吡哆醇盐酸盐物理化学性质

[ 密度 ]:
1.201g/cm3

[ 沸点 ]:
414.1ºC at 760 mmHg

[ 熔点 ]:
274°C(dec.)(lit.)

[ 分子式 ]:
C₈H₁₂ClNO₂

[ 分子量 ]:
189.64

[ 闪点 ]:
204.2ºC

[ 精确质量 ]:
189.055649

[ PSA ]:
53.35000

[ LogP ]:
1.69830

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 蒸汽压 ]:
1.34E-07mmHg at 25°C

[ 储存条件 ]:
−20°C

4-脱氧吡哆醇盐酸盐MSDS

详细MSDS(安全技术说明书)

4-脱氧吡哆醇盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UT4800000

CHEMICAL NAME :: 3-Pyridinemethanol, 4,6-dimethyl-5-hydroxy-, hydrochloride

CAS REGISTRY NUMBER :: 148-51-6

LAST UPDATED :: 199012

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C8-H11-N-O2.Cl-H

MOLECULAR WEIGHT :: 189.66

WISWESSER LINE NOTATION :: T6NJ B1 CQ D1 E1Q &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 1570 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 17,1235,1974 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 11500 ug/kg

SEX/DURATION :: female 1-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 169,1329,1970

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 11500 ug/kg

SEX/DURATION :: female 1-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - body wall Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 169,1329,1970

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 11500 ug/kg

SEX/DURATION :: female 1-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow) Reproductive - Specific Developmental Abnormalities - endocrine system

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 169,1329,1970

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4-脱氧吡哆醇盐酸盐安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
UT4800000

[ 海关编码 ]:
2933399090

4-脱氧吡哆醇盐酸盐海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-脱氧吡哆醇盐酸盐文献

Effect of combination of deoxypyridoxine with known anti-proliferative or immunosuppressive agents on lymphocyte serine hydroxymethyltransferase.

Postgrad. Med. J. 70 Suppl 1 , S89-92, (1994)

Measurements of serine hydroxymethyltransferase (SHMT) in resting lymphocyte cultures showed that the level of activity of this enzyme is very low. Under the influence of mitogenic stimuli serine hydr...

Intracellular predominance of the pyridoxal 5'-phosphate form of aspartate aminotransferase in Escherichia coli B and reversible transformation of this form by extracellular substances.

Biochimie 71(4) , 427-38, (1989)

The intracellular proportion of the pyridoxal 5'-phosphate form of aspartate aminotransferase to the total enzyme in E. coli B cells was determined by a newly devised method, dependent on selective in...

Effects of DL-alpha-difluoromethylornithine, 4-deoxypyridoxine and methylglyoxal bis(guanylhydrazone) on allograft prolongation.

Life Sci. 48(3) , 225-35, (1991)

DL-alpha-difluoromethylornithine (DFMO), 4-deoxypyridoxine (4-DOP), and methylglyoxal bis (guanylhydrazone) (MGBG) were tested as inhibitors of acute skin graft rejection. Proximal full thickness tail...

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