氟甲噻嗪

氟甲噻嗪名称

[ CAS 号 ]:
148-56-1

[ 中文名 ]:
氟甲噻嗪

[ 英文名 ]:
2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-(trifluoromethyl)-, 1,1-dioxide

[英文别名 ]:

Trifluoromethylthiazide
Flumethazide
Trifluomethylthiazide
Fludemil
Ademol
Ademil
Flumetiazid
EINECS 205-717-4
Flumethiazid
Routrax

氟甲噻嗪物理化学性质

[ 密度 ]:
1.99g/cm3

[ 沸点 ]:
560ºC at 760mmHg

[ 分子式 ]:
C₈H₆F₃N₃O₄S₂

[ 分子量 ]:
329.27600

[ 精确质量 ]:
328.97500

[ PSA ]:
135.45000

[ LogP ]:
2.93080

[ 折射率 ]:
1.673

氟甲噻嗪毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DK9800000

CHEMICAL NAME :: 4H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-(trifluoromethyl)-, 1,1-dioxide

CAS REGISTRY NUMBER :: 148-56-1

LAST UPDATED :: 199601

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C8-H6-F3-N3-O4-S2

MOLECULAR WEIGHT :: 329.29

WISWESSER LINE NOTATION :: T66 BSWM ENJ HXFFF ISZW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >8 gm/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 134,273,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1760 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 134,273,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 910 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 128,405,1960

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氟甲噻嗪安全信息

[ 海关编码 ]:
2935009090

氟甲噻嗪海关

[ 海关编码 ]: 2935009090

[ 中文概述 ]:
2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:35.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%