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3-羟基丁酸钠

3-羟基丁酸钠用途

3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) 是一种在 I 型糖尿病中升高的代谢物。3-Hydroxybutyric acid sodium 可以调节膜脂的性质。

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3-羟基丁酸钠名称

[ CAS 号 ]:
150-83-4

[ 中文名 ]:
3-羟基丁酸钠

[ 英文名 ]:
3-Hydroxybutyric acid sodium

[英文别名 ]:

Sodium 3-hydroxybutanoate
EINECS 205-774-5
Butanoic acid, 3-hydroxy-, sodium salt (1:1)
MFCD00016716
DL-3-HYDROXYBUTYRIC ACID SODIUM SALT
Sodium (3R)-3-hydroxybutanoate
sodium 3-hydroxybutyrate
UNII:19AN4ZH292

3-羟基丁酸钠生物活性

[ 描述 ]:

3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) 是一种在 I 型糖尿病中升高的代谢物。3-Hydroxybutyric acid sodium 可以调节膜脂的性质。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

[体外研究]

3-羟基丁酸钠(β-羟基丁酸钠)能够与脂质相互作用(用DPPC单层模拟)并在临床浓度下改变相行为。3-羟基丁酸钠也降低了DPPC单分子膜的界面粘度[1]。

[参考文献]

[1]. Hsu TT, et al. 3-Hydroxybutyric acid interacts with lipid monolayers at concentrations that impair consciousness. Langmuir. 2013 Feb 12;29(6):1948-55.

3-羟基丁酸钠物理化学性质

[ 沸点 ]:
269.2ºC at 760mmHg

[ 熔点 ]:
165-167ºC

[ 分子式 ]:
C₄H₇NaO₃

[ 分子量 ]:
126.086

[ 闪点 ]:
121ºC

[ 精确质量 ]:
126.029289

[ PSA ]:
60.36000

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 蒸汽压 ]:
0.000979mmHg at 25°C

[ 储存条件 ]:
2-8°C

3-羟基丁酸钠MSDS

3-羟基丁酸钠安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
205-774-5

[ 海关编码 ]:
2918199090

3-羟基丁酸钠合成路线

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3-羟基丁酸钠下游产品

3-羟基丁酸钠海关

[ 海关编码 ]: 2918199090

[ 中文概述 ]:
HS: 2918199090. 其他含醇基但不含其他含氧基羧酸（包括其酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

3-羟基丁酸钠文献

Hormone and Cytokine Responses to Repeated Endotoxin Exposures-No Evidence of Endotoxin Tolerance After 5 Weeks in Humans.

Shock 44 , 32-5, (2015)

Endotoxin administrations are used in experimental models of inflammatory disease. Short-term endotoxin tolerance in response to repeated endotoxin exposure is well known, but the duration of endotoxi...

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