sodium (6R,7R)-7-[[(E)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino] -3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-ca rboxylate

名称

[ 英文名 ]:
sodium (6R,7R)-7-[[(E)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino] -3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-ca rboxylate

物理化学性质

[ 沸点 ]:
936ºC at 760mmHg

[ 分子式 ]:
C₁₇H₁₈N₅NaO₆S₂

[ 分子量 ]:
475.47400

[ 闪点 ]:
519.9ºC

[ 精确质量 ]:
475.06000

[ PSA ]:
234.31000

[ LogP ]:
0.62820

[ 蒸汽压 ]:
0mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XI0327000

CHEMICAL NAME :: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy) methyl)-7-((2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl) amino)-8-oxo-, monosodium salt(6R-(6-alpha,7-beta(Z)))-

CAS REGISTRY NUMBER :: 152824-70-9

LAST UPDATED :: 199607

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C17-H18-N5-O6-S2.Na

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 27300 mg/kg/30D-I

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in adrenal weight Biochemical - Metabolism (Intermediary) - lipids including transport

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 24,1175,1993

点击显示