多依雌酸

多依雌酸名称

[ CAS 号 ]:
15372-34-6

[ 中文名 ]:
多依雌酸

[ 英文名 ]:
2-Phenanthrenecarboxylicacid, 1-ethyl-1,2,3,4-tetrahydro-7-methoxy-2-methyl-, (1R,2S)-rel-

[英文别名 ]:

Bdda me
Dl-cis-bisdehydrodoisynolic acid methyl ether
Doisynoestrol

多依雌酸物理化学性质

[ 密度 ]:
1.136g/cm3

[ 沸点 ]:
480ºC at 760mmHg

[ 分子式 ]:
C₁₉H₂₂O₃

[ 分子量 ]:
298.37600

[ 闪点 ]:
172.4ºC

[ 精确质量 ]:
298.15700

[ PSA ]:
46.53000

[ LogP ]:
4.37910

[ 蒸汽压 ]:
0mmHg at 25°C

[ 折射率 ]:
1.582

[ 储存条件 ]:
库房通风低温干燥

多依雌酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VS3040000

CHEMICAL NAME :: 16,17-Seco-13-alpha-estra-1,3,5,7,9-pentaen-17-oic acid, 3-methoxy-, (+-)-

CAS REGISTRY NUMBER :: 15372-34-6

LAST UPDATED :: 199801

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H22-O3

MOLECULAR WEIGHT :: 298.41

WISWESSER LINE NOTATION :: L B666&&TJ EO1 K2 LVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 17500 ng/kg

SEX/DURATION :: female 7 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 3,387,1971

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 300 ug/kg

SEX/DURATION :: female 7-9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 3,387,1971

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2400 ug/kg

SEX/DURATION :: female 6 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 4,15,1971

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2 mg/kg

SEX/DURATION :: female 1-6 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 115,101,1973

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