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N-芴甲氧羰酰基-2,2,4,6,7-五甲基二氢苯并呋喃-5-磺酰-L-精氨酸

用途

Fmoc-Arg(Pbf)-OH是一种含有胺保护基团Fmoc的精氨酸衍生物。Fmoc-Arg(Pbf)-OH是将Arg引入SPPS(固相肽合成)的基础[1]。

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名称

[ CAS 号 ]:
154445-77-9

[ 中文名 ]:
Fmoc-Pbf-L-精氨酸

[ 英文名 ]:
FMOC-Arg(Pbf)-OH

[中文别名 ]:

[英文别名 ]:

Nalpha-Fmoc-Nomega-Pbf-L-arginine
Nα-Fmoc-Nω-Pbf-L-arginine
Na-Fmoc-Nw-Pbf-L-arginine
Fmoc-Arg(Pbf)-OH
MFCD00235804
Fmoc-L-Arg(Pbf)-OH

生物活性

[ 描述 ]:

Fmoc-Arg(Pbf)-OH是一种含有胺保护基团Fmoc的精氨酸衍生物。Fmoc-Arg(Pbf)-OH是将Arg引入SPPS(固相肽合成)的基础[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Beatriz G, et al. Successful development of a method for the incorporation of Fmoc-Arg (Pbf)-OH in solid-phase peptide synthesis using N-butylpyrrolidinone (NBP) as solvent. Green Chemistry, 2020, 22(10): 3162-3169.

物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 熔点 ]:
132°C

[ 分子式 ]:
C₃₄H₄₀N₄O₇S

[ 分子量 ]:
648.769

[ 精确质量 ]:
648.261780

[ PSA ]:
175.29000

[ LogP ]:
6.86

[ 外观性状 ]:
白色或灰白色粉末

[ 折射率 ]:
1.649

[ 储存条件 ]:
<0°C;避免加热

[ 水溶解性 ]:
可溶于：二甲基甲酰胺

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ 海关编码 ]:
2932999099

海关

[ 海关编码 ]: 2932999099

[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

文献

Chemical synthesis of a polypeptide backbone derived from the primary sequence of the cancer protein NY-ESO-1 enabled by kinetically controlled ligation and pseudoprolines.

Biopolymers 104 , 116-27, (2015)

The cancer protein NY-ESO-1 has been shown to be one of the most promising vaccine candidates although little is known about its cellular function. Using a chemical protein strategy, the 180 amino aci...

A new class of peptidomimetics targeting the polo-box domain of Polo-like kinase 1.

J. Med. Chem. 58(1) , 294-304, (2015)

Recent progress in the development of peptide-derived Polo-like kinase (Plk1) polo-box domain (PBD) inhibitors has led to the synthesis of multiple peptide ligands with high binding affinity and selec...

Internalization of Near-Infrared Fluorescently Labeled Activatable Cell-Penetrating Peptide and of Proteins into Human Fibrosarcoma Cell Line HT-1080.

J. Cell. Biochem. 116 , 1222-31, (2015)

The internalization of near-infrared fluorescently labeled cargos into living cells and tissues allows a highly sensitive detection without interference from skin, porphins or other fluorescent cell a...

更多文献

N-芴甲氧羰酰基-2,2,4,6,7-五甲基二氢苯并呋喃-5-磺酰-L-精氨酸

用途

名称

生物活性

物理化学性质

MSDS

详细MSDS(安全技术说明书)

安全信息

海关

文献

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