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2,4-二氨基嘧啶

2,4-二氨基嘧啶名称

[ CAS 号 ]:
156-81-0

[ 中文名 ]:
2,4-二氨基嘧啶

[ 英文名 ]:
2,4-Diaminopyrimidine

[中文别名 ]:

2,4-氨基嘧啶

[英文别名 ]:

2,4(1H,3H)-Pyrimidinediimine
2,4-Pyrimidinediamine
MFCD00038023
2,3-DIPHENYL-6-NITROQUINOXALINE
2,4-diamino-pyrimidine
pyrimidinediamine
2,6-diaminopyrimidine
2,4-Diaminopyrimidine
Pyrimidine,2,4-diamino
diamino-pyrimidine

2,4-二氨基嘧啶物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
401.7±37.0 °C at 760 mmHg

[ 熔点 ]:
143-147 °C(lit.)

[ 分子式 ]:
C₄H₆N₄

[ 分子量 ]:
110.117

[ 闪点 ]:
225.6±13.7 °C

[ 精确质量 ]:
110.059242

[ PSA ]:
77.82000

[ LogP ]:
-0.64

[ 外观性状 ]:
淡橙色结晶粉末

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.695

[ 储存条件 ]:
Refrigerator (+4°C)

[ 水溶解性 ]:
840 g/L (25 ºC)

2,4-二氨基嘧啶MSDS

2,4-二氨基嘧啶安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2942000000

2,4-二氨基嘧啶合成路线

2,4-二氨基嘧啶上下游产品

2,4-二氨基嘧啶上游产品

2,4-二氨基嘧啶下游产品

2,4-二氨基嘧啶海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2,4-二氨基嘧啶文献

Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus.

Neuropharmacology 99 , 422-31, (2015)

Nitric oxide (NO) is involved in desensitization of μ-opioid receptors (MOR). We used extracellular recordings in vitro to unmask the NO-dependent pathways involved in MOR desensitization in the rat l...

Design and optimization of hybrid of 2,4-diaminopyrimidine and arylthiazole scaffold as anticancer cell proliferation and migration agents.

Eur. J. Med. Chem. 96 , 269-80, (2015)

Therapeutics of metastatic or triple-negative breast cancer are still challenging in clinical. Herein we demonstrated the design and optimization of a series of hybrid of 2,4-diaminopyrimidine and ary...

Cocrystals of 6-methyl-2-thiouracil: presence of the acceptor-donor-acceptor/donor-acceptor-donor synthon.

Acta Crystallogr. C Struct. Chem. 71(Pt 3) , 229-38, (2015)

The results of seven cocrystallization experiments of the antithyroid drug 6-methyl-2-thiouracil (MTU), C(5)H(6)N(2)OS, with 2,4-diaminopyrimidine, 2,4,6-triaminopyrimidine and 6-amino-3H-isocytosine ...

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