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2,2,6,6-四甲基哌啶-1-氧基-4-氨基-4-羧酸

2,2,6,6-四甲基哌啶-1-氧基-4-氨基-4-羧酸名称

[ CAS 号 ]:
15871-57-5

[ 中文名 ]:
2,2,6,6-四甲基吡啶-1-氧基-4-氨基-4-羧酸

[ 英文名 ]:
TOAC

[中文别名 ]:

[英文别名 ]:

MFCD00800575

2,2,6,6-四甲基哌啶-1-氧基-4-氨基-4-羧酸物理化学性质

[ 密度 ]:
1.1255 (rough estimate)

[ 沸点 ]:
355.55°C (rough estimate)

[ 熔点 ]:
230 °C

[ 分子式 ]:
C₁₀H₁₉N₂O₃

[ 分子量 ]:
215.26900

[ 精确质量 ]:
215.14000

[ PSA ]:
66.56000

[ LogP ]:
1.40520

[ 外观性状 ]:
Crystalline Powder | White to off-white

[ 折射率 ]:
1.4550 (estimate)

[ 储存条件 ]:
0-6°C

2,2,6,6-四甲基哌啶-1-氧基-4-氨基-4-羧酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi,Xn

[ 风险声明 (欧洲) ]:
36/37/38-22

[ 安全声明 (欧洲) ]:
37/39-26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
29333999

2,2,6,6-四甲基哌啶-1-氧基-4-氨基-4-羧酸合成路线

详细合成路线

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2,2,6,6-四甲基哌啶-1-氧基-4-氨基-4-羧酸文献

In silico interpretation of cw-ESR at 9 and 95 GHz of mono- and bis- TOAC-labeled Aib-homopeptides in fluid and frozen acetonitrile.

J. Phys. Chem. B 115(44) , 13026-36, (2011)

In this paper, we address the interpretation of molecular properties of selected singly and doubly spin-labeled peptides from continuous-wave electron spin resonance (cw-ESR) spectroscopy. This study ...

Intramembrane water associated with TOAC spin-labeled alamethicin: electron spin-echo envelope modulation by D2O.

Biophys. J. 96(3) , 997-1007, (2009)

Alamethicin is a 20-residue, hydrophobic, helical peptide, which forms voltage-sensitive ion channels in lipid membranes. The helicogenic, nitroxyl amino acid TOAC was substituted isosterically for Ai...

Probing the helical tilt and dynamic properties of membrane-bound phospholamban in magnetically aligned bicelles using electron paramagnetic resonance spectroscopy.

Biochim. Biophys. Acta 1818(3) , 645-50, (2012)

Wild-type phospholamban (WT-PLB), a Ca(2+)-ATPase (SERCA) regulator in the sarcoplasmic reticulum membrane, was studied using TOAC nitroxide spin labeling, magnetically aligned bicelles, and electron ...

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