N-methyl-N-pyridin-2-ylnitrous amide
N-methyl-N-pyridin-2-ylnitrous amide名称
[ CAS 号 ]:
16219-98-0
[ 英文名 ]:
N-methyl-N-pyridin-2-ylnitrous amide
[英文别名 ]:
- N-methyl-N-nitrosopyridin-2-amine
- 2-N-nitrosomethylaminopyridine
- 2-Nitrosomethylaminopyridine
- methyl-nitroso-pyridin-2-yl-amine
- N-Methyl-N-nitroso-2-aminopyridine
- N-Nitroso-N-methyl-2-aminopyridine
- Pyridine,2-nitrosomethylamino
N-methyl-N-pyridin-2-ylnitrous amide物理化学性质
[ 密度 ]:
1.17g/cm3
[ 沸点 ]:
286.6ºC at 760mmHg
[ 分子式 ]:
C6H7N3O
[ 分子量 ]:
137.13900
[ 闪点 ]:
127.1ºC
[ 精确质量 ]:
137.05900
[ PSA ]:
45.56000
[ LogP ]:
1.19920
[ 蒸汽压 ]:
0.00262mmHg at 25°C
[ 折射率 ]:
1.569
N-methyl-N-pyridin-2-ylnitrous amide毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UT6386000
- CHEMICAL NAME :
- Pyridine, 2-nitrosomethylamino-
- CAS REGISTRY NUMBER :
- 16219-98-0
- BEILSTEIN REFERENCE NO. :
- 0118228
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C6-H7-N3-O
- MOLECULAR WEIGHT :
- 137.16
- WISWESSER LINE NOTATION :
- T6NJ BN1&NO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - ulceration or bleeding from stomach Gastrointestinal - ulceration or bleeding from large intestine
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg/50W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Liver - tumors
MUTATION DATA
- TYPE OF TEST :
- Host-mediated assay
- TEST SYSTEM :
- Rodent - mouse Bacteria - Escherichia coli
- DOSE/DURATION :
- 60 mg/kg
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,415,1982
N-methyl-N-pyridin-2-ylnitrous amide合成路线
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