Tazettine,6a-deoxy-8-hydroxy-, hydrochloride, (6ab,8b)- (9CI)
名称
[ CAS 号 ]:
17322-85-9
[ 英文名 ]:
Tazettine,6a-deoxy-8-hydroxy-, hydrochloride, (6ab,8b)- (9CI)
[英文别名 ]:
- isotazettine,hydrochloride
- Tazettine,6a-deoxy-8-hydroxy-,(6abeta,8beta)
- (+)-pretazettine
- Pretazettin
- isotazettine
- pratazettine hydrochloride
- Pretazettin-hydrochlorid
物理化学性质
[ 沸点 ]:
499.6ºC at 760mmHg
[ 分子式 ]:
C18H22ClNO5
[ 分子量 ]:
367.82400
[ 闪点 ]:
255.9ºC
[ 精确质量 ]:
367.11900
[ PSA ]:
60.39000
[ LogP ]:
2.07160
[ 蒸汽压 ]:
8.45E-11mmHg at 25°C
[ 折射率 ]:
1.656
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU7500000
- CHEMICAL NAME :
- Pretazettine, hydrochloride
- CAS REGISTRY NUMBER :
- 17322-85-9
- LAST UPDATED :
- 198207
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H21-N-O5.Cl-H
- MOLECULAR WEIGHT :
- 367.86
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 47 mg/kg
- TOXIC EFFECTS :
- Cardiac - pulse rate Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- PWPSA8 Proceedings of the Western Pharmacology Society. (Univ. of California Dept. of Pharmacology, Los Angeles, CA 90024) V.1- 1958- Volume(issue)/page/year: 24,259,1981
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