p-AMINOBENZOIC ACID-3-(DIETHYLAMINO) PROPYL ESTER HYDROCHLORIDE

名称

[ CAS 号 ]:
17599-08-5

[ 英文名 ]:
p-AMINOBENZOIC ACID-3-(DIETHYLAMINO) PROPYL ESTER HYDROCHLORIDE

[英文别名 ]:

3-(4-aminobenzoyl)oxypropyl-diethylazanium

物理化学性质

[ 密度 ]:
1.061g/cm3

[ 沸点 ]:
387.1ºC at 760 mmHg

[ 分子式 ]:
C₁₄H₂₃ClN₂O₂

[ 分子量 ]:
286.79800

[ 闪点 ]:
187.9ºC

[ 精确质量 ]:
286.14500

[ PSA ]:
55.56000

[ LogP ]:
3.54070

[ 蒸汽压 ]:
3.36E-06mmHg at 25°C

[ 折射率 ]:
1.537

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG2300000

CHEMICAL NAME :: Benzoic acid, p-amino-, 3-(diethylamino)propyl ester, hydrochloride

CAS REGISTRY NUMBER :: 17599-08-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C14-H22-N2-O2.Cl-H

MOLECULAR WEIGHT :: 286.84

WISWESSER LINE NOTATION :: ZR DVO3N2&2 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 17,1012,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 24,159,1925

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