2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺
2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺名称
[ CAS 号 ]:
17615-73-5
[ 中文名 ]:
2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺
[ 英文名 ]:
5-amino-2-(4-aminophenyl)sulfonylbenzenesulfonamide
[英文别名 ]:
- Sulfamoyldapsone
- 5-Amino-2-sulfanilyl-benzolsulfonsaeure-amid
- Metanilamide,6-sulfanilyl
- 6-(p-Anilinosulfonyl)metanilamide
- SDDS
- 2-Sulfamonyl-4,4'-diaminophenylsulfone
- 2-Sulfamonyl-4,4'-diaminodiphenyl-sulfone
- 5-amino-2-sulfanilyl-benzenesulfonic acid amide
2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺物理化学性质
[ 密度 ]:
1.549g/cm3
[ 沸点 ]:
686.1ºC at 760mmHg
[ 分子式 ]:
C12H13N3O4S2
[ 分子量 ]:
327.37900
[ 闪点 ]:
368.7ºC
[ 精确质量 ]:
327.03500
[ PSA ]:
163.10000
[ LogP ]:
4.35550
[ 蒸汽压 ]:
1.12E-18mmHg at 25°C
[ 折射率 ]:
1.681
[ 储存条件 ]:
库房通风低温干燥
2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OY2230000
- CHEMICAL NAME :
- Metanilamide, 6-sulfanilyl-
- CAS REGISTRY NUMBER :
- 17615-73-5
- BEILSTEIN REFERENCE NO. :
- 3435880
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C12-H13-N3-O4-S2
- MOLECULAR WEIGHT :
- 327.40
- WISWESSER LINE NOTATION :
- ZSWR CZ FSWR DZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6 gm/kg
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - other changes
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >6 gm/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes Blood - pigmented or nucleated red blood cells Blood - changes in leukocyte (WBC) count
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5150 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Skin and Appendages - hair
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Mammal - pig
- DOSE/DURATION :
- >213 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 24 gm/kg
- SEX/DURATION :
- female 9-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 9,695,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1800 mg/kg
- SEX/DURATION :
- female 9-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 9,695,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 120 mg/kg
- SEX/DURATION :
- female 9-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 9,695,1975
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2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺安全信息
[ 海关编码 ]:
2935009090
2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺上下游产品
2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺上游产品
2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺下游产品
2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺海关
[ 海关编码 ]: 2935009090
[ 中文概述 ]:
2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
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相关化合物
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