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十四烷基—β-D麦芽糖苷

十四烷基—β-D麦芽糖苷用途

十四烷基-β-D-麦芽糖苷是一种吸收促进剂,可增加常规人胰岛素或速效胰岛素类似物赖氨酸胰岛素的鼻腔吸收[1]。

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十四烷基—β-D麦芽糖苷名称

[ CAS 号 ]:
18449-82-6

[ 中文名 ]:
十四烷基-β-D-麦芽糖苷

[ 英文名 ]:
n-tetradecyl-beta-d-maltoside

[中文别名 ]:

十四烷基-Β-D-麦芽糖苷

[英文别名 ]:

tetradecylmaltoside
n-Tetradecyl |A-D-maltopyranoside
Tetradecyl-|A-D-maltoside

十四烷基—β-D麦芽糖苷生物活性

[ 描述 ]:

十四烷基-β-D-麦芽糖苷是一种吸收促进剂,可增加常规人胰岛素或速效胰岛素类似物赖氨酸胰岛素的鼻腔吸收[1]。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[参考文献]

[1]. Arnold JJ, et al. Reestablishment of the nasal permeability barrier to several peptides following exposure to the absorption enhancer tetradecyl-beta-D-maltoside. J Pharm Sci. 2010 Apr;99(4):1912-20.

十四烷基—β-D麦芽糖苷物理化学性质

[ 分子式 ]:
C₂₆H₅₀O₁₁

[ 分子量 ]:
538.66900

[ 精确质量 ]:
538.33500

[ PSA ]:
178.53000

[ LogP ]:
0.32820

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
H2O: soluble10mg/mL, clear, colorless

十四烷基—β-D麦芽糖苷MSDS

详细MSDS(安全技术说明书)

十四烷基—β-D麦芽糖苷安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

十四烷基—β-D麦芽糖苷文献

Synthetic long-chain alkyl maltosides and alkyl sucrose esters as enhancers of nasal insulin absorption.

J. Pharm. Sci. 91(6) , 1456-1462, (2002)

A series of new glycosides with extended alkyl side-chains (C(13-16)) linked to maltose or sucrose were synthesized and tested for their efficacy in enhancing nasal insulin absorption in anesthetized ...

Pathway of detergent-mediated and peptide ligand-mediated refolding of heterodimeric class II major histocompatibility complex (MHC) molecules.

Eur. J. Biochem. 248(3) , 684-691, (1997)

We investigated the mechanism of refolding and reassembly of recombinant alpha and beta chains of the class II major histocompatibility molecules (MHC-II) HLA-DRB5*0101. Both chains were expressed in ...

Modulation of acetylcholinesterase activity by glycoside-detergents and their solubilization efficiency for neuronal membranes from bovine nucleus caudatus.

Biochem. Biophys. Res. Commun. 106(3) , 848-855, (1982)

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