Rp-8-bromo-PET-Cyclic GMPS sodium salt

Rp-8-bromo-PET-Cyclic GMPS sodium salt用途

Rp-8-bromo-PET-Cyclic GMPS sodium salt is a cell permeable, competitive, and reversible inhibitor of cGMP-dependent protein kinases (cGKs) that blocks activation of cGKI and cGKII by cGMP.

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Rp-8-bromo-PET-Cyclic GMPS sodium salt名称

[ CAS 号 ]:
185246-32-6

[ 中文名 ]:
Rp-8-bromo-PET-Cyclic GMPS sodium salt

[ 英文名 ]:
Rp-8-Br-PET-cGMPs

Rp-8-bromo-PET-Cyclic GMPS sodium salt物理化学性质

[ 熔点 ]:
240-300ºC(lit.)

[ 分子式 ]:
C₁₈H₁₆BrN₅NaO₇PS

[ 分子量 ]:
580.28100

[ 精确质量 ]:
578.95900

[ PSA ]:
190.09000

[ LogP ]:
2.71680

[ 储存条件 ]:
-20°C，密闭，干燥

Rp-8-bromo-PET-Cyclic GMPS sodium saltMSDS

详细MSDS(安全技术说明书)

Rp-8-bromo-PET-Cyclic GMPS sodium salt安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

Rp-8-bromo-PET-Cyclic GMPS sodium salt文献

B-type natriuretic peptide inhibits angiotensin II-induced proliferation and migration of pulmonary arterial smooth muscle cells.

Pediatr. Pulmonol. 49(8) , 734-44, (2014)

Pulmonary vascular remodeling, characterized by disordered proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs), is a pathognomonic feature of pulmonary arterial hypertension...

GLAST/EAAT1 regulation in cultured Bergmann glia cells: role of the NO/cGMP signaling pathway.

Neurochem. Int. 73 , 139-45, (2014)

Glutamate, the major excitatory amino acid, activates a wide variety of signal transduction cascades. Ionotropic and metabotropic glutamate receptors are critically involved in long-term synaptic chan...

The NO-cGMP-PKG signaling pathway coordinately regulates ERK and ERK-driven gene expression at pre- and postsynaptic sites following LTP-inducing stimulation of thalamo-amygdala synapses.

Neural Plast. 2010 , 540940, (2011)

Long-term potentiation (LTP) at thalamic input synapses to the lateral nucleus of the amygdala (LA) has been proposed as a cellular mechanism of the formation of auditory fear memories. We have previo...

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