二苯并[A,E]芘
二苯并[A,E]芘名称
[ CAS 号 ]:
192-65-4
[ 中文名 ]:
二苯并[A,E]芘
[ 英文名 ]:
dibenzo[a,e]pyrene
[中文别名 ]:
[英文别名 ]:
- Dibenzo[f,pqr]tetraphene
- dibenzo(a,e)pyrene
- dibenzo[a,e]pyrene
- Naphtho[1,2,3,4-def]chrysene
二苯并[A,E]芘物理化学性质
[ 密度 ]:
1.3±0.1 g/cm3
[ 沸点 ]:
552.3±17.0 °C at 760 mmHg
[ 熔点 ]:
233.5ºC
[ 分子式 ]:
C24H14
[ 分子量 ]:
302.368
[ 闪点 ]:
282.0±15.1 °C
[ 精确质量 ]:
302.109558
[ LogP ]:
7.63
[ 外观性状 ]:
黄色针状晶体
[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C
[ 折射率 ]:
1.913
[ 储存条件 ]:
2-8°C
二苯并[A,E]芘MSDS
二苯并[A,E]芘毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QL0175000
- CHEMICAL NAME :
- Naphtho(1,2,3,4-def)chrysene
- CAS REGISTRY NUMBER :
- 192-65-4
- BEILSTEIN REFERENCE NO. :
- 2054070
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C24-H14
- MOLECULAR WEIGHT :
- 302.38
- WISWESSER LINE NOTATION :
- L D66 L666 B6 2AB A&J
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 312 mg/kg/52W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 72 mg/kg/9W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 25 nmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 342,9,1995 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 3,201,1973 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,327,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,327,1983 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993
二苯并[A,E]芘安全信息
[ 符号 ]:
GHS05, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H341-H350
[ 警示性声明 ]:
P201-P202-P281-P308 + P313-P405-P501
[ 危害码 (欧洲) ]:
Xn
[ 风险声明 (欧洲) ]:
40-41
[ 安全声明 (欧洲) ]:
26-39
[ 危险品运输编码 ]:
UN 2811
[ RTECS号 ]:
QL0175000
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1(b)
[ 海关编码 ]:
2902909090
二苯并[A,E]芘合成路线
二苯并[A,E]芘制备
1. 从二甲苯中得淡黄色针晶
二苯并[A,E]芘海关
[ 海关编码 ]: 2902909090
[ 中文概述 ]:
2902909090. 其他芳香烃. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:2.0%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量
[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%
二苯并[A,E]芘文献
Rep. Carcinog. 12 , 353-61, (2011)
Determination of 23 polycyclic aromatic hydrocarbons in atmospheric particulate matter of the Paris area and photolysis by sunlight.
Int. J. Environ. Anal. Chem. 19(2) , 111-31, (1985)
Twenty-three polycyclic aromatic hydrocarbons (PAH) were determined in atmospheric particulate matter in 4 places of the Paris area at several times of the year. Fractionation was performed by reverse...
Dibenzo[a,e]pyrene.IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 32 , 327-30, (1983)
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