吗喹酮

吗喹酮名称

[ CAS 号 ]:
19395-58-5

[ 中文名 ]:
吗喹酮

[ 英文名 ]:
moquizone

[英文别名 ]:

吗喹酮物理化学性质

[ 密度 ]:
1.278g/cm3

[ 沸点 ]:
599.9ºC at 760 mmHg

[ 分子式 ]:
C20H21N3O3

[ 分子量 ]:
351.39900

[ 闪点 ]:
316.6ºC

[ 精确质量 ]:
351.15800

[ PSA ]:
53.09000

[ LogP ]:
2.03760

[ 蒸汽压 ]:
2.37E-14mmHg at 25°C

[ 折射率 ]:
1.618

吗喹酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA3150000
CHEMICAL NAME :
4(1H)-Quinazolinone, 2,3-dihydro-1-(morpholinoacetyl)-3-phenyl-
CAS REGISTRY NUMBER :
19395-58-5
LAST UPDATED :
199612
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C20-H21-N3-O3
MOLECULAR WEIGHT :
351.44
WISWESSER LINE NOTATION :
T66 BVN EN DHJ CR& EV1- AT6N DOTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2220 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Vascular - regional or general arteriolar or venous dilation Lungs, Thorax, or Respiration - other changes
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 16,571,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
146 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 16,571,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
930 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 22,235,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
559 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 16,571,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
774 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 16,571,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
237 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 16,571,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1730 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Vascular - regional or general arteriolar or venous dilation Lungs, Thorax, or Respiration - other changes
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 16,571,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 16,571,1970
点击显示

推荐生产厂家/供应商:

暂无推荐供应商。请联系客服获知如何成为推荐供应商。


相关化合物

【吗喹酮】化源网提供吗喹酮CAS号19395-58-5,吗喹酮MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询吗喹酮上化源网,专业又轻松。>>电脑版:吗喹酮

标题:吗喹酮_密度_沸点_分子量_吗喹酮CAS号【19395-58-5】_化源网 地址:https://m.chemsrc.com/mip/cas/19395-58-5_415529.html