11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-ol

名称

[ CAS 号 ]:
1977-15-7

[ 英文名 ]:
11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-ol

[英文别名 ]:

2-Hydroxydesmethylimipramine
2-hydroxy-desipramine

物理化学性质

[ 密度 ]:
1.117g/cm3

[ 沸点 ]:
477.9ºC at 760mmHg

[ 熔点 ]:
146-148ºC

[ 分子式 ]:
C₁₈H₂₂N₂O

[ 分子量 ]:
282.38000

[ 闪点 ]:
242.8ºC

[ 精确质量 ]:
282.17300

[ PSA ]:
35.50000

[ LogP ]:
3.69430

[ 蒸汽压 ]:
9.32E-10mmHg at 25°C

[ 折射率 ]:
1.596

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HO2990000

CHEMICAL NAME :: 5H-Dibenz(b,f)azepin-2-ol, 10,11-dihydro-5-(3-(methylamino)propyl)-

CAS REGISTRY NUMBER :: 1977-15-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H22-N2-O

MOLECULAR WEIGHT :: 282.42

WISWESSER LINE NOTATION :: T C676 BN&T&J B3M1 FQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 31 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 15,187,1966

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安全信息

[ 海关编码 ]:
2933990090

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海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%