5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)

5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)名称

[ CAS 号 ]:
19893-78-8

[ 中文名 ]:
5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)

[ 英文名 ]:
N-(6-amino-3-methyl-2,4-dioxo-1H-pyrimidin-5-yl)acetamide

[英文别名 ]:

5-acetamido-6-amino-3-methyluracil
AAMU
5-Ammu
5-Acetylamino-6-amino-3-methyluracil

5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)物理化学性质

[ 密度 ]:
1.45g/cm3

[ 熔点 ]:
≥305ºC

[ 分子式 ]:
C₇H₁₀N₄O₃

[ 分子量 ]:
198.17900

[ 精确质量 ]:
198.07500

[ PSA ]:
109.98000

[ 折射率 ]:
1.606

5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933599090

5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)合成路线

详细合成路线

5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)上下游产品

5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)上游产品

5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)下游产品

5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-乙酰氨基-6-氨基-3-甲基尿嘧啶(AAMU)文献

Caffeine as a metabolic probe: validation of its use for acetylator phenotyping.

Clin. Pharmacol. Ther. 49(6) , 648-57, (1991)

The use of two caffeine metabolite ratios for acetylator phenotyping was validated by demonstrating concordance with two sulfamethazine tests in 178 unrelated healthy subjects. The caffeine metabolite...

An alternative test for acetylator phenotyping with caffeine.

Clin. Pharmacol. Ther. 42(5) , 509-13, (1987)

Previously published methods allow the determination of the genetically controlled acetylator status using caffeine as a test drug, based on the urinary excretion of a ring-opened metabolite of caffei...

Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment.

J. Chromatogr. B. Biomed. Sci. Appl. 755(1-2) , 73-84, (2001)

Urinary metabolic ratios of caffeine are used in humans to assess the enzymatic activities of cytochrome P450 isoenzyme 1A2 (CYP1A2), xanthine oxidase (XO) and for phenotyping individuals for the bimo...

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