1-NITRO-9-(3-DIMETHYLAMINOPROPYL-AMINE)-ACRIDINE-N-OXIDE DIHYDRO-CHLORIDE
名称
[ CAS 号 ]:
20064-00-0
[ 英文名 ]:
1-NITRO-9-(3-DIMETHYLAMINOPROPYL-AMINE)-ACRIDINE-N-OXIDE DIHYDRO-CHLORIDE
物理化学性质
[ 沸点 ]:
555.4ºC at 760mmHg
[ 分子式 ]:
C18H21ClN4O3
[ 分子量 ]:
376.83700
[ 闪点 ]:
289.7ºC
[ 精确质量 ]:
376.13000
[ PSA ]:
100.17000
[ LogP ]:
5.09150
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AR9245000
- CHEMICAL NAME :
- Acridine, 9-((3-(dimethylamino)propyl)amino)-1-nitro-, N-oxide, dihydrochloride
- CAS REGISTRY NUMBER :
- 20064-00-0
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C18-H20-N4-O3.2Cl-H
- MOLECULAR WEIGHT :
- 413.34
- WISWESSER LINE NOTATION :
- T C666 BNJ GNW IM3KO&1&1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 356 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- MMDPA6 Materia Medica Polona (English Edition). (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1969- Volume(issue)/page/year: 8,252,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5600 ug/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- MMDPA6 Materia Medica Polona (English Edition). (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1969- Volume(issue)/page/year: 8,252,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- MMDPA6 Materia Medica Polona (English Edition). (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1969- Volume(issue)/page/year: 8,252,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6200 ug/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- MMDPA6 Materia Medica Polona (English Edition). (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1969- Volume(issue)/page/year: 8,252,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 6250 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting
- REFERENCE :
- AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 28,777,1980
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