N-(2,3-dichlorophenyl)cyclohexanecarboxamide

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
429.3±35.0 °C at 760 mmHg

[ 分子式 ]:
C₁₃H₁₅Cl₂NO

[ 分子量 ]:
272.170

[ 闪点 ]:
213.4±25.9 °C

[ 精确质量 ]:
271.053070

[ LogP ]:
3.94

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.597

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 危险品运输编码 ]:
NONH for all modes of transport

Similarities and Distinctions in Actions of Surface-Directed and Classic Androgen Receptor Antagonists.

PLoS ONE 10(9) , e0137103, (2015)

The androgen receptor (AR) surface-directed antagonist MJC13 inhibits AR function and proliferation of prostate cancer (PC) cells. These effects are related to arrest of an AR/chaperone complex in the...

The FKBP52 Cochaperone Acts in Synergy with β-Catenin to Potentiate Androgen Receptor Signaling.

PLoS ONE 10(7) , e0134015, (2015)

FKBP52 and β-catenin have emerged in recent years as attractive targets for prostate cancer treatment. β-catenin interacts directly with the androgen receptor (AR) and has been characterized as a co-a...

Quantification of a New Anti-Cancer Molecule MJC13 Using a Rapid, Sensitive, and Reliable Liquid Chromatography-Tandem Mass Spectrometry Method.

Am. J. Mod. Chromatogr. 1(1) , 1-11, (2014)

MJC13 is a novel molecule that has potential use for the treatment of hormone refractory prostate cancer (HRPC). The purpose of this work was to develop a liquid chromatography-tandem mass spectrometr...

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