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1,2-二硬脂酰-锡-甘油-3-磷酸-rac-(1-甘油) 钠盐

用途

1,2-二硬脂酰-sn-甘油-3-磷脂酰甘油(钠)是用于药物递送的脂质体的成分[1]。

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名称

[ CAS 号 ]:
200880-42-8

[ 中文名 ]:
1,2-二硬脂酰基-sn-甘油-3-磷酸-(1'-rac-甘油)(钠盐)

[ 英文名 ]:
UNII:771667Q09X

[英文别名 ]:

18:0 PG
DSPG-Na
L-|A-Phosphatidyl-DL-glycerol,distearoyl
1,2-distearoyl-sn-glycero-3-phosphoglycerol
UNII:771667Q09X

生物活性

[ 描述 ]:

1,2-二硬脂酰-sn-甘油-3-磷脂酰甘油(钠)是用于药物递送的脂质体的成分[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Momtazi-Borojeni AA, et al. Negatively-charged Liposome Nanoparticles Can Prevent Dyslipidemia and Atherosclerosis Progression in the Rabbit Model. Curr Vasc Pharmacol. 2022;20(1):69-76.

物理化学性质

[ 沸点 ]:
480.0 °C

[ 熔点 ]:
90.27 °C

[ 分子式 ]:
C₄₂H₈₂NaO₁₀P

[ 分子量 ]:
801.058

[ 精确质量 ]:
800.554321

[ PSA ]:
161.46000

[ LogP ]:
11.88940

[ 外观性状 ]:
白色粉末

[ 储存条件 ]:
-20°C，避光，密封，惰性气体

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Nematic liquid crystals confined in microcapillaries for imaging phenomena at liquid-liquid interfaces.

Soft Matter 11 , 6999-7004, (2015)

Here, we report the development of an experimental system based on liquid crystals (LCs) confined in microcapillaries for imaging interfacial phenomena. The inner surfaces of the microcapillaries were...

Distearoyl phosphatidylglycerol liposomes improve surface and transport properties of CF mucus.

Eur. Respir. J. 6 , 1156, (1993)

We have previously shown that a decreased level of phosphatidylglycerol in cystic fibrosis (CF) respiratory mucus is partly responsible for its marked adhesiveness and stickiness, which impair mucus t...

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