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2-氨乙基吗啉

2-氨乙基吗啉用途

有机合成。

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2-氨乙基吗啉名称

[ CAS 号 ]:
2038-03-1

[ 中文名 ]:
N-(2-氨基乙基)吗啉

[ 英文名 ]:
2-Morpholinoethanamine

[中文别名 ]:

[英文别名 ]:

2-morpholinoethan-1-amine
N-2-Aminoethylmorfolin [Czech]
EINECS 218-011-6
N-Aminoethylmorpholine
N-(2-aminoethyl)-morpholine
2-(N-morpholino)ethylamine
2-(morpholin-4-yl)-ethyl amine
MFCD00006182
4-(2-aminoethyl)-morpholine
4-MORPHOLINEETHANAMINE

2-氨乙基吗啉物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
202.6±20.0 °C at 760 mmHg

[ 熔点 ]:
24 °C

[ 分子式 ]:
C₆H₁₄N₂O

[ 分子量 ]:
130.188

[ 闪点 ]:
76.3±21.8 °C

[ 精确质量 ]:
130.110611

[ PSA ]:
38.49000

[ LogP ]:
-1.01

[ 外观性状 ]:
透明无色至淡黄色液体在熔点后

[ 蒸汽压 ]:
0.3±0.4 mmHg at 25°C

[ 折射率 ]:
1.474

[ 储存条件 ]:
库房通风低温干燥

[ 水溶解性 ]:
soluble

2-氨乙基吗啉MSDS

2-氨乙基吗啉毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD7350000

CHEMICAL NAME :: Morpholine, 4-(2-aminoethyl)-

CAS REGISTRY NUMBER :: 2038-03-1

BEILSTEIN REFERENCE NO. :: 0104378

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C6-H14-N2-O

MOLECULAR WEIGHT :: 130.22

WISWESSER LINE NOTATION :: T6N DOTJ A2Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,888,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,888,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2145 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 109,108,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 300 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1251 No. of Facilities: 119 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 2625 (estimated) No. of Female Employees: 597 (estimated)

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2-氨乙基吗啉安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H314-H317

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T:Toxic;C:Corrosive;

[ 风险声明 (欧洲) ]:
R22;R24;R34;R43

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 2735 8/PG 2

[ WGK德国 ]:
2

[ RTECS号 ]:
QD7350000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2934999090

2-氨乙基吗啉合成路线

2-氨乙基吗啉上下游产品

2-氨乙基吗啉上游产品

2-氨乙基吗啉下游产品

2-氨乙基吗啉海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-氨乙基吗啉文献

Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.

Bioorg. Med. Chem. 16 , 3530-6, (2008)

The first activation study of the human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms associated to tumors, hCA IX and XII, with a small library of natural and non-natural amino acids as well as aroma...

Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.

Bioorg. Med. Chem. Lett. 16 , 3955-9, (2006)

The first activation study of isoform XIII of carbonic anhydrase (CA, EC 4.2.1.1) is reported. A series of amino acids and amines incorporating protonatable moieties of the primary/heterocyclic amine ...

Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines.

Bioorg. Med. Chem. 15 , 5351-7, (2007)

The secretory isozyme of human carbonic anhydrase (hCA, EC 4.2.1.1), hCA VI, has been cloned, expressed, and purified in a bacterial expression system. The kinetic parameters for the CO(2) hydration r...

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