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5-羧基-X-罗丹明琥珀酰亚胺酯

5-羧基-X-罗丹明琥珀酰亚胺酯用途

5-羧基-X-罗丹明N-琥珀酰亚胺酯是一种标记试剂。5-羧基-X-罗丹明N-琥珀酰亚胺酯可用于制备电荷修饰染料标记的双脱氧核苷酸三磷酸(ddNTP)“直接加载”DNA测序[1]。

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5-羧基-X-罗丹明琥珀酰亚胺酯名称

[ CAS 号 ]:
209734-74-7

[ 中文名 ]:
5-羧基-X-罗丹明琥珀酰亚胺酯(单一化合物)

[ 英文名 ]:
ROX-SE

[中文别名 ]:

5-羧基-X-罗丹明 SE

[英文别名 ]:

5-carboxy-X-rhodamine succinimidyl ester

5-羧基-X-罗丹明琥珀酰亚胺酯生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Finn PJ, Sun L, Nampalli S, Xiao H, Nelson JR, Mamone JA, Grossmann G, Flick PK, Fuller CW, Kumar S. Synthesis and application of charge-modified dye-labeled dideoxynucleoside-5'-triphosphates to 'direct-load' DNA sequencing. Nucleic Acids Res. 2002 Jul 1;30(13):2877-85.

5-羧基-X-罗丹明琥珀酰亚胺酯物理化学性质

[ 分子式 ]:
C₃₇H₃₃N₃O₇

[ 分子量 ]:
631.67400

[ 精确质量 ]:
631.23200

[ PSA ]:
123.43000

[ LogP ]:
4.58390

[ 储存条件 ]:
-20°C

5-羧基-X-罗丹明琥珀酰亚胺酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

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5-羧基-X-罗丹明琥珀酰亚胺酯文献

High-resolution liquid chromatography of fluorescent dye-labeled nucleic acids.

Anal. Biochem. 223 , 39, (1994)

Using 100 mM of triethylammonium acetate as ion-pairing reagent, phosphodiester oligonucleotides labeled fluorescently at their 5' terminus could be separated successfully on alkylated nonporous 2.3-m...

DNA sequencing with dye-labeled terminators and T7 DNA polymerase: effect of dyes and dNTPs on incorporation of dye-terminators and probability analysis of termination fragments.

Nucleic Acids Res. 20 , 2471, (1992)

The incorporation of fluorescently labeled dideoxynucleotides by T7 DNA polymerase is optimized by the use of Mn2+, fluorescein analogs and four 2'-deoxyribonucleoside 5'-O-(1-thiotriphosphates) (dNTP...

Synthesis and application of charge-modified dye-labeled dideoxynucleoside-5'-triphosphates to 'direct-load' DNA sequencing.

Nucleic Acids Res. 30 , 2877, (2002)

A novel series of charge-modified, dye-labeled 2',3'-dideoxynucleoside-triphosphate terminators were synthesized and evaluated as reagents for DNA sequencing. These terminators possess an advantage ov...

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