Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11b,16a)-
名称
[ CAS 号 ]:
2135-14-0
[ 英文名 ]:
Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11b,16a)-
[英文别名 ]:
- Descinolone acetonide
物理化学性质
[ 密度 ]:
1.27g/cm3
[ 沸点 ]:
538.2ºC at 760mmHg
[ 分子式 ]:
C24H31FO5
[ 分子量 ]:
418.49800
[ 闪点 ]:
279.3ºC
[ 精确质量 ]:
418.21600
[ PSA ]:
72.83000
[ LogP ]:
3.44640
[ 蒸汽压 ]:
0mmHg at 25°C
[ 折射率 ]:
1.573
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU3840000
- CHEMICAL NAME :
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(ox y))-, (11-beta,16-alpha)-
- CAS REGISTRY NUMBER :
- 2135-14-0
- BEILSTEIN REFERENCE NO. :
- 0056899
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C24-H31-F-O5
- MOLECULAR WEIGHT :
- 418.55
- WISWESSER LINE NOTATION :
- L E5 B666 OV AHTTT&J A1 BF CQ E1 FV1Q FOVR& G1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 194 mg/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,250,1966
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相关化合物
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