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2-甲鳥苷

2-甲鳥苷用途

N2-Methylguanosine 是一种修饰的核苷,修饰发生在 tRNA 的几个特定位点。

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2-甲鳥苷名称

[ CAS 号 ]:
2140-77-4

[ 中文名 ]:
N2-甲基鸟苷

[ 英文名 ]:
N-Methylguanosine

[中文别名 ]:

2-甲鳥苷

[英文别名 ]:

2-Methylguanosine
Guanosine, N-methyl-
N-Methylguanosine
Guanosine,N-methyl
2-N-Methylguanosine
N(2)-Methylguanosine

2-甲鳥苷生物活性

[ 描述 ]:

N2-Methylguanosine 是一种修饰的核苷,修饰发生在 tRNA 的几个特定位点。

[ 相关类别 ]:

信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物

研究领域 >> 其他

[参考文献]

[1]. Ginell SL, et al. Conformation of N2-methylguanosine, a modified nucleoside of tRNA. Biochem Biophys Res Commun. 1978 Oct 30;84(4):886-94.

2-甲鳥苷物理化学性质

[ 密度 ]:
2.0±0.1 g/cm3

[ 沸点 ]:
709.5ºC at 760mmHg

[ 熔点 ]:
233 °C (decomp)(Solv: water (7732-18-5))

[ 分子式 ]:
C₁₁H₁₅N₅O₅

[ 分子量 ]:
297.267

[ 闪点 ]:
382.9ºC

[ 精确质量 ]:
297.107330

[ PSA ]:
145.52000

[ LogP ]:
-3.09

[ 蒸汽压 ]:
3.99E-21mmHg at 25°C

[ 折射率 ]:
1.850

[ 储存条件 ]:
2-8°C

2-甲鳥苷MSDS

2-甲鳥苷安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

2-甲鳥苷合成路线

2-甲鳥苷文献

Exometabolom analysis of breast cancer cell lines: Metabolic signature.

Sci. Rep. 5 , 13374, (2015)

Cancer cells show characteristic effects on cellular turnover and DNA/RNA modifications leading to elevated levels of excreted modified nucleosides. We investigated the molecular signature of differen...

Artificial receptors for the extraction of nucleoside metabolite 7-methylguanosine from aqueous media made by molecular imprinting.

J. Chromatogr. A. 1365 , 12-8, (2014)

A series of imprinted polymers targeting nucleoside metabolites, prepared using a template analogue approach, are presented. These were prepared following selection of the optimum functional monomer b...

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase.

Proc. Natl. Acad. Sci. U. S. A. 106 , 3484-3489, (2009)

The N7-methylguanosine (m7G) cap is the defining structural feature of eukaryotic mRNAs. Most eukaryotic viruses that replicate in the cytoplasm, including coronaviruses, have evolved strategies to ca...

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2-甲鳥苷

2-甲鳥苷用途

2-甲鳥苷名称

2-甲鳥苷生物活性

2-甲鳥苷物理化学性质

2-甲鳥苷MSDS

详细MSDS(安全技术说明书)

2-甲鳥苷安全信息

2-甲鳥苷合成路线

详细合成路线

2-甲鳥苷文献

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