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5-硝基-4,6-二羟基嘧啶

5-硝基-4,6-二羟基嘧啶用途

【用途一】
用作医药中间体
【用途二】
该品为有机合成中间体。经氯化、胺化可得4,6-二氨基-5-硝基嘧啶。

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5-硝基-4,6-二羟基嘧啶名称

[ CAS 号 ]:
2164-83-2

[ 中文名 ]:
5-硝基-4,6-二羟基嘧啶

[ 英文名 ]:
5-nitropyrimidine-4,6-diol

[中文别名 ]:

[英文别名 ]:

4,6-Pyrimidinediol, 5-nitro-
6-Hydroxy-5-nitro-4(1H)-pyrimidinone
5-Nitro-4,6-pyrimidinediol
EINECS 218-504-6
5-nitropyrimidine-4,6-diol
5-nitro-1H-pyrimidine-4,6-dione
MFCD00006110
5-Nitro-4,6-dihydroxypyrimidine
4,6-Dihydroxy-5-nitropyriMidine
4,6-Dihydroxy-5-nitropyrimdine

5-硝基-4,6-二羟基嘧啶物理化学性质

[ 密度 ]:
1.9±0.1 g/cm3

[ 沸点 ]:
303.5±37.0 °C at 760 mmHg

[ 熔点 ]:
>300 °C(lit.)

[ 分子式 ]:
C₄H₃N₃O₄

[ 分子量 ]:
157.084

[ 闪点 ]:
137.4±26.5 °C

[ 精确质量 ]:
157.012360

[ PSA ]:
112.06000

[ LogP ]:
-0.73

[ 外观性状 ]:
黄色结晶粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.701

[ 储存条件 ]:
室温，干燥

5-硝基-4,6-二羟基嘧啶MSDS

5-硝基-4,6-二羟基嘧啶安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933599090

5-硝基-4,6-二羟基嘧啶合成路线

5-硝基-4,6-二羟基嘧啶制备

由4,6-二羟基嘧啶经硝化而得

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5-硝基-4,6-二羟基嘧啶海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-硝基-4,6-二羟基嘧啶文献

Phenobarbital induction and chemical synergism demonstrate the role of UDP-glucuronosyltransferases in detoxification of naphthalophos by Haemonchus contortus larvae.

Antimicrob. Agents Chemother. 58(12) , 7475-83, (2014)

We used an enzyme induction approach to study the role of detoxification enzymes in the interaction of the anthelmintic compound naphthalophos with Haemonchus contortus larvae. Larvae were treated wit...

Inhibition of UDP-glucuronyltransferase activity in rat liver microsomes by pyrimidine derivatives.

Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. 112(3) , 321-5, (1995)

Thirty-one differently substituted pyrimidine bases were tested for their inhibitory effect on the glucuronidation of 4-nitrophenol and phenolphthalein by rat liver microsomes. 5-Nitrouracil (compound...

The activity of thymidine phosphorylase obtained from human uterine leiomyomas and studied in the presence of pyrimidine derivatives.

Z. Naturforsch., C, J. Biosci. 52(9-10) , 670-5, (1997)

Partially purified samples of thymidine phosphorylase were obtained from four preparations of human uterine leiomyomas and uteri using the method of Yoshimura et al. (1990), Biochim. Biophys. Acta 103...

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