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二苯并[c,h] ac啶

二苯并[c,h] ac啶名称

[ CAS 号 ]:
224-53-3

[ 中文名 ]:
二苯并[C,H]吖啶

[ 英文名 ]:
Dibenzo[c,h]acridine

[英文别名 ]:

Dibenzo[c,h]acridine
1,2:7,8-dibenzacridine
Dibenz[c,h]acridine
3,4,5,6-dibenzacridine

二苯并[c,h] ac啶物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
534.0±19.0 °C at 760 mmHg

[ 熔点 ]:
191ºC

[ 分子式 ]:
C₂₁H₁₃N

[ 分子量 ]:
279.335

[ 闪点 ]:
240.3±14.1 °C

[ 精确质量 ]:
279.104797

[ PSA ]:
12.89000

[ LogP ]:
5.86

[ 外观性状 ]:
粉末

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.824

[ 储存条件 ]:
2-8°C

二苯并[c,h] ac啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HN1225000

CHEMICAL NAME :: Dibenz(c,h)acridine

CAS REGISTRY NUMBER :: 224-53-3

BEILSTEIN REFERENCE NO. :: 0209259

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C21-H13-N

MOLECULAR WEIGHT :: 279.35

WISWESSER LINE NOTATION :: T E6 D6 B666 CNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2040 mg/kg/85W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4400 mg/kg/65W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg/25W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 4 ug/plate

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,873,1978 *** REVIEWS *** TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Pc,4,1972

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二苯并[c,h] ac啶安全信息

[ 海关编码 ]:
2933990090

二苯并[c,h] ac啶合成路线

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二苯并[c,h] ac啶海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

二苯并[c,h] ac啶文献

Dose-dependent differences in the profile of mutations induced by carcinogenic (R,S,S,R) bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons.

Adv. Exp. Med. Biol. 500 , 697-707, (2001)

Chinese hamster V79 cells were exposed to a high or low concentration of the highly carcinogenic (R,S,S,R) or the less active (S,R,R,S) bay- or fjord-region diol epoxides of benzo[a]pyrene, benzo[c]ph...

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