醋替罗酯

醋替罗酯用途

Acetiromate 是一种甲状腺素类似物。Acetiromate 是一种抗血脂药物,用于高脂血症。
点击显示

醋替罗酯名称

[ CAS 号 ]:
2260-08-4

[ 中文名 ]:
醋替罗酯

[ 英文名 ]:
Acetiromate

[英文别名 ]:

醋替罗酯生物活性

[ 描述 ]:

Acetiromate 是一种甲状腺素类似物。Acetiromate 是一种抗血脂药物,用于高脂血症。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他
研究领域 >> 代谢疾病

[参考文献]

[1]. S Kumaoka. Long-term administration of 3,5-diodo-4(3'-iodo4'-acetoxyphenoxy) benzoic acid (acetiromate) in hyperlipidemic patients. Endocrinol Jpn. 1974 Aug;21(4):355-60.  

醋替罗酯物理化学性质

[ 密度 ]:
2.351 g/cm3

[ 沸点 ]:
561.2ºC at 760 mmHg。 产品描述 安全性：

[ 分子式 ]:
C15H9I3O5

[ 分子量 ]:
649.94200

[ 闪点 ]:
293.2ºC

[ 精确质量 ]:
649.75800

[ PSA ]:
72.83000

[ LogP ]:
4.91620

[ 蒸汽压 ]:
1.96E-13mmHg at 25°C

[ 折射率 ]:
1.724

醋替罗酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG8597700
CHEMICAL NAME :
Benzoic acid, 3,5-diiodo-4-(4-hydroxy-3-iodophenoxy)-, acetate
CAS REGISTRY NUMBER :
2260-08-4
LAST UPDATED :
198706
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C15-H9-I3-O5
MOLECULAR WEIGHT :
649.94

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 5,383,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
480 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 16,431,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
520 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 5,383,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 5,383,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 5,383,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 16,431,1974
点击显示

推荐生产厂家/供应商：

暂无推荐供应商。请联系客服获知如何成为推荐供应商。

相关化合物

【醋替罗酯】化源网提供醋替罗酯CAS号2260-08-4，醋替罗酯MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询醋替罗酯上化源网，专业又轻松。>>电脑版：醋替罗酯

标题：醋替罗酯_用途_密度_沸点_醋替罗酯CAS号【2260-08-4】_化源网 地址：https://m.chemsrc.com/mip/cas/2260-08-4_754313.html