溴琥胺

溴琥胺名称

[ CAS 号 ]:
22855-57-8

[ 中文名 ]:
溴琥胺

[ 英文名 ]:
Brosuximide

[英文别名 ]:

3-(3-Bromophenyl)-2,5-pyrrolidinedione
Brosuximide
Brosuximida [INN-Spanish]
2-(m-Bromophenyl)succinimide
Imid kwasu 3-bromofenylobursztynowego [Polish]
3-Bromophenylsuccinimide
3-(3-bromophenyl)-pyrrolidine-2,5-dione
m-Bromophenylsuccinimide
Succinimide,2-(m-bromophenyl)
Brosuximidum [INN-Latin]

溴琥胺物理化学性质

[ 密度 ]:
1.606g/cm3

[ 沸点 ]:
425.7ºC at 760mmHg

[ 分子式 ]:
C₁₀H₈BrNO₂

[ 分子量 ]:
254.08000

[ 闪点 ]:
211.2ºC

[ 精确质量 ]:
252.97400

[ PSA ]:
49.66000

[ LogP ]:
1.85510

[ 蒸汽压 ]:
1.88E-07mmHg at 25°C

[ 折射率 ]:
1.601

溴琥胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WN2285000

CHEMICAL NAME :: Succinimide, 2-(m-bromophenyl)-

CAS REGISTRY NUMBER :: 22855-57-8

BEILSTEIN REFERENCE NO. :: 1457286

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H8-Br-N-O2

MOLECULAR WEIGHT :: 254.10

WISWESSER LINE NOTATION :: T5VMVTJ DR CE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 40,657,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 370 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 23,593,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 920 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 39,475,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 310 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 13,465,1978

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溴琥胺安全信息

[ 海关编码 ]:
2925190090

溴琥胺海关

[ 海关编码 ]: 2925190090

[ 中文概述 ]:
2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

溴琥胺