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头孢氨苄

头孢氨苄用途

Cefalexin一水合物是头孢菌素类抗生素。

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头孢氨苄名称

[ CAS 号 ]:
23325-78-2

[ 中文名 ]:
头孢氨苄(一水物)

[ 英文名 ]:
Cephalexin monohydrate

[中文别名 ]:

[英文别名 ]:

EINECS 239-773-6
Cephalexin monohydrate
MFCD00167148
Cefalexin（compacted）
Cefalexin Monohydrate

头孢氨苄生物活性

[ 描述 ]:

Cefalexin一水合物是头孢菌素类抗生素。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[参考文献]

[1]. Speight TM, et al. Cephalexin: a review of its antibacterial, pharmacological and therapeutic properties. Drugs. 1972;3(1):9-78.

[2]. Tanrisever B, et al. Cefadroxil. A review of its antibacterial, pharmacokinetic and therapeutic properties in comparison with cephalexin and cephradine. Drugs. 1986;32 Suppl 3:1-16.

[相关活性小分子]

头孢氨苄物理化学性质

[ 密度 ]:
1.5g/cm3

[ 沸点 ]:
727.4ºC at 760 mmHg

[ 分子式 ]:
C₁₆H₁₉N₃O₅S

[ 分子量 ]:
383.850

[ 闪点 ]:
393.7ºC

[ 精确质量 ]:
383.070648

[ PSA ]:
147.26000

[ LogP ]:
1.40970

[ 外观性状 ]:
白色结晶固体带有苦味道

[ 蒸汽压 ]:
3.27E-22mmHg at 25°C

[ 折射率 ]:
154 ° (C=0.5, H2O)

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
NH4OH 1 M: 50 mg/mL, clear, yellow

头孢氨苄MSDS

详细MSDS(安全技术说明书)

头孢氨苄安全信息

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R42/43

[ 安全声明 (欧洲) ]:
22-36/37-45

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
XI0350000

头孢氨苄文献

Interaction of Bordetella pertussis filamentous hemagglutinin with human TLR2: identification of the TLR2-binding domain.

APMIS 123(2) , 156-62, (2015)

Filamentous hemagglutinin (FHA) is a major adhesion and virulence factor of Bordetella pertussis and also a main component of acellular pertussis vaccines. Interaction of FHA with different receptors ...

Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.

PLoS Pathog. 11(2) , e1004645, (2015)

The identification of Mycobacterium tuberculosis genes necessary for persistence in vivo provides insight into bacterial biology as well as host defense strategies. We show that disruption of M. tuber...

Purification and characterization of the Staphylococcus aureus bacillithiol transferase BstA.

Biochim. Biophys. Acta 1840(9) , 2851-61, (2014)

Gram-positive bacteria in the phylum Firmicutes synthesize the low molecular weight thiol bacillithiol rather than glutathione or mycothiol. The bacillithiol transferase YfiT from Bacillus subtilis wa...

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