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2-氨基茚满盐酸盐

2-氨基茚满盐酸盐名称

[ CAS 号 ]:
2338-18-3

[ 中文名 ]:
2-氨基茚满盐酸盐

[ 英文名 ]:
2-aminoindane HCl

[中文别名 ]:

2-茚满胺盐酸盐

[英文别名 ]:

2-indanylaminehydrochloride
2-aminoindane HCl
Indan-2-aminium chloride
2-INDANAMINE HCL
2,3-dihydro-1H-inden-2-amine hydrochloride (1:1)
2-Aminoindane hydrochloride
2-Indanamine hydrochloride
2-Indanamine hydrochloride (1:1)
Indan-2-amine hydrochloride (1:1)
MFCD00012549

2-氨基茚满盐酸盐物理化学性质

[ 密度 ]:
1.056g/cm3

[ 沸点 ]:
226.2ºC at 760mmHg

[ 熔点 ]:
245-247 °C(lit.)

[ 分子式 ]:
C₉H₁₂ClN

[ 分子量 ]:
169.651

[ 闪点 ]:
96.8ºC

[ 精确质量 ]:
169.065826

[ PSA ]:
26.02000

[ LogP ]:
2.61480

[ 外观性状 ]:
灰白色粉末

[ 蒸汽压 ]:
0.0831mmHg at 25°C

[ 储存条件 ]:
库房通风低温干燥

2-氨基茚满盐酸盐MSDS

2-氨基茚满盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NK4050000

CHEMICAL NAME :: 2-Indanamine, hydrochloride

CAS REGISTRY NUMBER :: 2338-18-3

LAST UPDATED :: 199606

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C9-H11-N.Cl-H

MOLECULAR WEIGHT :: 169.67

WISWESSER LINE NOTATION :: L56T&J CZ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 326 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 36300 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - analgesia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 133,400,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 170 mg/kg

TOXIC EFFECTS :: Behavioral - analgesia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 133,400,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 158 mg/kg

TOXIC EFFECTS :: Behavioral - analgesia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 133,400,1961

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - analgesia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 133,400,1961 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 405 mg/kg/30D-I

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Gastrointestinal - nausea or vomiting

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 132,400,1961

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2-氨基茚满盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
NK4050000

[ 包装等级 ]:
I; II; III

[ 海关编码 ]:
2921499090

2-氨基茚满盐酸盐合成路线

2-氨基茚满盐酸盐上下游产品

2-氨基茚满盐酸盐上游产品

2-氨基茚满盐酸盐下游产品

2-氨基茚满盐酸盐海关

[ 海关编码 ]: 2921499090

[ 中文概述 ]:
2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

2-氨基茚满盐酸盐文献

Central cyanosis on a psychiatric unit treated at the Salford Royal Hospital.

Thorax 69(12) , 1157-8, (2014)

We describe a case of acquired methaemoglobinaemia due to frequent use of the 'legal high' known as 'Pink Panthers'. This contains 5,6-Methylenedioxy-2-aminoindane and 2-Aminoindane, both amphetamine ...

Oxygen-18 studies on the oxidative deamination mechanism of alicyclic primary amines in rabbit liver microsomes.

Arch. Biochem. Biophys. 215(2) , 433-43, (1982)

Assessment of a potential dopaminergic prodrug moiety in several ring systems.

J. Med. Chem. 29(10) , 2016-20, (1986)

The ortho hydroxy/methyl, hydroxy/hydroxymethyl, hydroxy/formyl, and hydroxy/carboxy substitution patterns, some of which confer dopaminergic agonist effects upon 2-aminotetralin ring systems, have be...

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