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U-99194 maleate salt

U-99194 maleate salt用途

U-99194 maleate is a potent, selective D3 antagonist.

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U-99194 maleate salt名称

[ CAS 号 ]:
234757-41-6

[ 中文名 ]:
U 99194马来酸酯(PNU 99194)

[ 英文名 ]:
U-99194 maleate

[英文别名 ]:

CRF (human,rat)

U-99194 maleate salt物理化学性质

[ 熔点 ]:
146 - 147 °C

[ 分子式 ]:
C₂₁H₃₁NO₆

[ 分子量 ]:
393.47400

[ 精确质量 ]:
393.21500

[ PSA ]:
96.30000

[ LogP ]:
3.00480

[ 外观性状 ]:
白色固体

[ 储存条件 ]:
室温

U-99194 maleate saltMSDS

详细MSDS(安全技术说明书)

U-99194 maleate salt安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

U-99194 maleate salt文献

Dopaminergic D2-like agonists produce yawning in the myelin mutant taiep and Sprague–Dawley rats

Pharmacol. Biochem. Behav. 102(1) , 118-23, (2012)

Systemic administration of D2-like dopaminergic-receptor agonists increases yawning behavior. However, only a few studies have been done in animals with pathological conditions. The taiep rat is a mye...

Presynaptic dopaminergic agonists increased gripping-generated immobility episodes in the myelin-mutant taiep rat.

Neurosci. Lett. 483(3) , 189-92, (2010)

The taiep rat is a myelin mutant whose immobility episodes (IEs) can be caused by gripping them by the tail. Electroencephalographic recordings during IEs show a rapid-eye movement sleep-like pattern,...

The dopamine D3-receptor: a postsynaptic receptor inhibitory on rat locomotor activity.

J. Neural Transm. Gen. Sect. 94 , 11-19, (1993)

We report on the pharmacological effects of the 20 fold D3 vs. D2 dopamine receptor preferring compound U99194A. It is shown that U99194A increases rat locomotor activity at doses that do not increase...

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