苯氟雷司

苯氟雷司用途

Benfluorex Hydrochloride, a hypolipidemic and an anorectic agent, has been considered to treat people with type 2 diabetes by improving glycemic control and decreasing insulin resistance.

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苯氟雷司名称

[ CAS 号 ]:
23602-78-0

[ 中文名 ]:
苯氟雷司

[ 英文名 ]:
Benfluorex

[中文别名 ]:

[英文别名 ]:

s992
Mediaxal
jp992
BENFLUREX
Minolip
se780
s780

苯氟雷司物理化学性质

[ 密度 ]:
1.183g/cm3

[ 沸点 ]:
420.5ºC at 760 mmHg

[ 分子式 ]:
C₁₉H₂₁ClF₃NO₂

[ 分子量 ]:
387.82400

[ 闪点 ]:
208.1ºC

[ 精确质量 ]:
387.12100

[ PSA ]:
38.33000

[ LogP ]:
5.27590

[ 蒸汽压 ]:
2.81E-07mmHg at 25°C

[ 折射率 ]:
1.515

苯氟雷司MSDS

苯氟雷司毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KL8275000

CHEMICAL NAME :: Ethanol, 2-(alpha-methyl-m-trifluoromethylphenethylamino)-, benzoate

CAS REGISTRY NUMBER :: 23602-78-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H20-F3-N-O2

MOLECULAR WEIGHT :: 351.40

WISWESSER LINE NOTATION :: FXFFR CY1&1M2OVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 17XKAB "International Symposium on Amphetamines and Related Compounds, Proceedings, Mario Negri Institute for Pharmacological Research, Milan, 1969," Costa, E., and S. Garattini, eds., New York, Raven Press, 1970 Volume(issue)/page/year: -,21,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 108 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 17XKAB "International Symposium on Amphetamines and Related Compounds, Proceedings, Mario Negri Institute for Pharmacological Research, Milan, 1969," Costa, E., and S. Garattini, eds., New York, Raven Press, 1970 Volume(issue)/page/year: -,21,1970

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苯氟雷司安全信息

[ WGK德国 ]:
2

[ RTECS号 ]:
KL8275000

[ 海关编码 ]:
2922199090

苯氟雷司合成路线

苯氟雷司上下游产品

苯氟雷司上游产品

苯氟雷司下游产品

苯氟雷司海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%