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DL-邻酪氨酸

DL-邻酪氨酸用途

DL-O-酪氨酸是一种酪氨酸衍生物[1]。

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DL-邻酪氨酸名称

[ CAS 号 ]:
2370-61-8

[ 中文名 ]:
DL-o-络氨酸

[ 英文名 ]:
DL-O-Tyrosine

[中文别名 ]:

[英文别名 ]:

2,5-Diaminopentanoic acid
EINECS 219-134-8
2-Amino-3-(2-hydroxyphenyl)propionic Acid
L-2,5-Diaminopentanoic acid
MFCD00021725
D,L-o-tyrosine
DL-o-Tyrosine

DL-邻酪氨酸生物活性

[ 描述 ]:

DL-O-酪氨酸是一种酪氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

DL-邻酪氨酸物理化学性质

[ 密度 ]:
1.333g/cm3

[ 沸点 ]:
369ºC at 760mmHg

[ 熔点 ]:
260ºC

[ 分子式 ]:
C₉H₁₁NO₃

[ 分子量 ]:
181.18900

[ 闪点 ]:
177ºC

[ 精确质量 ]:
181.07400

[ PSA ]:
83.55000

[ LogP ]:
1.04690

[ 外观性状 ]:
灰白色固体

[ 蒸汽压 ]:
5.14E-18mmHg at 25°C

[ 储存条件 ]:
-20°C Freezer

[ 水溶解性 ]:
Soluble in water, and DMSO (Heated).

DL-邻酪氨酸MSDS

详细MSDS(安全技术说明书)

DL-邻酪氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YP2285000

CHEMICAL NAME :: o-Tyrosine, DL-

CAS REGISTRY NUMBER :: 2370-61-8

LAST UPDATED :: 197901

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H11-N-O3

MOLECULAR WEIGHT :: 181.21

WISWESSER LINE NOTATION :: QVYZ1R BQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02426

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DL-邻酪氨酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
YP2285000

[ 海关编码 ]:
2922509090

DL-邻酪氨酸海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

DL-邻酪氨酸文献

Ion-pairing reversed-phase liquid chromatography fractionation in combination with isotope labeling reversed-phase liquid chromatography–mass spectrometry for comprehensive metabolome profiling

J. Chromatogr. A. 1218(23) , 3689-94, (2011)

We report a novel two-dimensional (2D) separation strategy aimed at improving the detectability of liquid chromatography mass spectrometry (LC–MS) for metabolome analysis. It is based on the use of io...

Concomitant tumor resistance: the role of tyrosine isomers in the mechanisms of metastases control.

Cancer Res. 72(5) , 1043-50, (2012)

Concomitant tumor resistance (CR) is a phenomenon in which a tumor-bearing host is resistant to the growth of secondary tumor implants and metastasis. Although previous studies indicated that T-cell-d...

Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.

J. Biol. Chem. 274(49) , 34621-8, (1999)

Oxidative stress is implicated in the death of dopaminergic neurons in Parkinson's disease and in the 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP) model of Parkinson's disease. Oxidative speci...

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