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7,10-二氨基苯并吖啶

7,10-二氨基苯并吖啶名称

[ CAS 号 ]:
2381-40-0

[ 中文名 ]:
7,10-二氨基苯并吖啶

[ 英文名 ]:
7,10-Dimethylbenzo[c]acridine

[中文别名 ]:

7,10-二甲基苯并[C]吖啶

[英文别名 ]:

6,9-Dimethyl-1,2-benzacridine
7,10-Dimethyl-benzo<c>acridin
7,10-Dimethylbenzo[c]acridine
Benz[c]acridine, 7,10-dimethyl-
2,10-Dimethyl-7,8-benzoacridin
7,10-Dimethylbenz<c>acridin

7,10-二氨基苯并吖啶物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
470.2±14.0 °C at 760 mmHg

[ 熔点 ]:
147-149ºC(lit.)

[ 分子式 ]:
C₁₉H₁₅N

[ 分子量 ]:
257.329

[ 闪点 ]:
209.8±12.7 °C

[ 精确质量 ]:
257.120453

[ PSA ]:
12.89000

[ LogP ]:
5.55

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.738

7,10-二氨基苯并吖啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU3485000

CHEMICAL NAME :: Benz(c)acridine, 7,10-dimethyl-

CAS REGISTRY NUMBER :: 2381-40-0

BEILSTEIN REFERENCE NO. :: 0192194

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C19-H15-N

MOLECULAR WEIGHT :: 257.35

WISWESSER LINE NOTATION :: T D6 B666 CNJ F J

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 190 mg/kg/16W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - bronchiolar constriction

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg/4W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg/10D-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Kidney

DOSE/DURATION :: 80 ug/L

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,873,1978

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7,10-二氨基苯并吖啶安全信息

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
20/21/22-36/37/38-40

[ 安全声明 (欧洲) ]:
S22;S26;S36

[ WGK德国 ]:
3

[ RTECS号 ]:
CU3485000

[ 海关编码 ]:
2933990090

7,10-二氨基苯并吖啶合成路线

详细合成路线

7,10-二氨基苯并吖啶上下游产品

7,10-二氨基苯并吖啶上游产品

7,10-二氨基苯并吖啶下游产品

7,10-二氨基苯并吖啶海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%