Benzeneacetic acid, a-ethoxy-a-phenyl-, 2-(dimethylamino)ethylester, hydrochloride (9CI)

名称

[ CAS 号 ]:
2424-75-1

[ 英文名 ]:
Benzeneacetic acid, a-ethoxy-a-phenyl-, 2-(dimethylamino)ethylester, hydrochloride (9CI)

[英文别名 ]:

Aestocin
Propalgyl
Dimenoxadol hydrochloride
Estocin

物理化学性质

[ 沸点 ]:
444.5ºC at 760mmHg

[ 分子式 ]:
C₂₀H₂₆ClNO₃

[ 分子量 ]:
363.87800

[ 闪点 ]:
222.6ºC

[ 精确质量 ]:
363.16000

[ PSA ]:
38.77000

[ LogP ]:
3.87350

[ 蒸汽压 ]:
4.26E-08mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AH2790000

CHEMICAL NAME :: Acetic acid, 2,2-diphenyl-2-ethoxy-, (2-(dimethylamino)ethyl) ester, hydrochloride

CAS REGISTRY NUMBER :: 2424-75-1

LAST UPDATED :: 199012

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H25-N-O3.Cl-H

MOLECULAR WEIGHT :: 363.92

WISWESSER LINE NOTATION :: 2OXR&R&VO2N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 66 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 8,189,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Behavioral - analgesia

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 4,7,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 179 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 32,317,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,571,1965

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安全信息

[ 海关编码 ]:
2922199090

海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%