1-乙酰基咪唑

【用途一】
用作医药中间体
【用途二】
作乙酰化试剂，供生化研究用。

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
222.0±23.0 °C at 760 mmHg

[ 熔点 ]:
99-105 °C(lit.)

[ 分子式 ]:
C₅H₆N₂O

[ 分子量 ]:
110.114

[ 闪点 ]:
88.0±22.6 °C

[ 精确质量 ]:
110.048012

[ PSA ]:
34.89000

[ LogP ]:
-0.34

[ 外观性状 ]:
白色至淡黄色晶体

[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C

[ 折射率 ]:
1.552

[ 储存条件 ]:
库房通风低温干燥

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

NI3400000

CHEMICAL NAME :

Imidazole, 1-acetyl-

CAS REGISTRY NUMBER :

2466-76-4

BEILSTEIN REFERENCE NO. :

0108425

LAST UPDATED :

199701

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C5-H6-N2-O

MOLECULAR WEIGHT :

110.13

WISWESSER LINE NOTATION :

T5N CNJ AV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

250 mg/kg

TOXIC EFFECTS :

Immunological Including Allergic - decreased immune response

REFERENCE :

StoGD# Personal Communication from G.D. Stoner, Dept. of Community Medicine, School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975 Volume(issue)/page/year: 27MAY1975 ** TUMORIGENIC DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

50 mg/kg/I

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :

JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,495,1975

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
NI3400000

[ 海关编码 ]:
2933290090

1-乙酰基咪唑上游产品

1-乙酰基咪唑下游产品

1.咪唑与乙酸异丙烯酯反应在50毫升圆烧瓶中，加入0.2g(0.03mol)咪唑，20ml乙酸异丙烯酯和几滴浓硫酸。将混合物在60℃保温1h。蒸馏除去少量的乙酸异丙烯酯和丙酮。剩余物用水碳酸钠处理。倾出液体。在空气浴中蒸发至干。得粗品3.1g，产率94%，熔点93-96℃。现经乙酸异丙烯酯重结晶，熔点达到101.5102.5℃。

[ 海关编码 ]: 2933290090

[ 中文概述 ]:
2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Involvement of conserved histidine, lysine and tyrosine residues in the mechanism of DNA cleavage by the caspase-3 activated DNase CAD.

Nucleic Acids Res. 30(6) , 1325-32, (2002)

The caspase-activated DNase (CAD) is involved in DNA degradation during apoptosis. Chemical modification of murine CAD with the lysine-specific reagent 2,4,6-trinitrobenzenesulphonic acid and the tyro...

Changes in the level and activation state of the plasma membrane H(+)-ATPase during aging of red beet slices.

Plant Physiol. 114(3) , 857-62, (1997)

The effect of aging on the plasma membrane (PM) H(+)-ATPase of red beet (Beta vulgaris L.) parenchyma discs was analyzed in PM purified by aqueous two-phase partitioning. Aging increased both the acti...

Chemical modification of active site residues in gamma-glutamyl transpeptidase. Aspartate 422 and cysteine 453.

J. Biol. Chem. 270(21) , 12476-80, (1995)

gamma-Glutamyl transpeptidase, an enzyme of central significance in glutathione metabolism, is inactivated by iodoacetamide, which esterifies an active site carboxyl group identified here as that of A...

更多文献

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：N-乙酰基咪唑

---

公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥138.0/25g ￥378.0/100g

联系人：刘佳

产品详情：1-乙酰咪唑

---

公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥29.9/5g ￥159.9/100g ￥45.9/25g ￥624.9/500g

联系人：阿拉丁

产品详情：1-乙酰咪唑

---

公司名：上海创赛科技有限公司

区域：上海市嘉定区

价格：
￥43.0/5g ￥97.0/25g ￥313.0/100g

联系人：夏言

产品详情：[Perfemiker]1-乙酰基咪唑,98%

---

公司名：中山市迪欣化工有限公司

区域：中山市三角镇

价格：
￥450.0/1000kg

联系人：陈雪萍

产品详情：1-乙酰基咪唑

---

查看所有供应商请点击：

1-乙酰基咪唑供应商