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分散蓝1

分散蓝1名称

[ CAS 号 ]:
2475-45-8

[ 中文名 ]:
分散兰1

[ 英文名 ]:
disperse blue 1

[中文别名 ]:

[英文别名 ]:

C.I. Disperse Blue 1
Celliton Blue G
DISPERSE BLUE 1
Amacel Blue GG
Serinyl Blue 2G
Perliton Blue B
Acetate Blue G
Fenacet Blue G
1,4,5,8-Tetraaminoanthraquinone
EINECS 219-603-7

分散蓝1物理化学性质

[ 密度 ]:
1.595 g/cm3

[ 沸点 ]:
711.9ºC at 760mmHg

[ 熔点 ]:
175-177 °C (anhydrous)(lit.)

[ 分子式 ]:
C₁₄H₁₂N₄O₂

[ 分子量 ]:
268.27100

[ 精确质量 ]:
268.09600

[ PSA ]:
138.22000

[ LogP ]:
3.11560

[ 蒸汽压 ]:
4.09E-20mmHg at 25°C

[ 折射率 ]:
1.857

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

分散蓝1MSDS

详细MSDS(安全技术说明书)

分散蓝1毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CB0540000

CHEMICAL NAME :: 9,10-Anthracenedione, 1,4,5,8-tetraamino-

CAS REGISTRY NUMBER :: 2475-45-8

BEILSTEIN REFERENCE NO. :: 0925672

LAST UPDATED :: 199710

DATA ITEMS CITED :: 20

MOLECULAR FORMULA :: C14-H12-N4-O2

MOLECULAR WEIGHT :: 268.30

WISWESSER LINE NOTATION :: L C666 BV IVJ DZ GZ KZ NZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5208 mg/kg/14D-C

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 54600 mg/kg/13W-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - inflammation, necrosis, or scarring of bladder Endocrine - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10416 mg/kg/14D-C

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 109200 mg/kg/13W-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 90125 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors Blood - leukemia

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 180 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Endocrine - tumors Reproductive - Tumorigenic effects - testicular tumors

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,203,1976 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,139,1990 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,123,1990 TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 14,433,1995 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0840 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 482 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0840 No. of Facilities: 4292 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 43522 (estimated) No. of Female Employees: 32059 (estimated)

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分散蓝1安全信息

[ 符号 ]:

GHS05, GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H315-H317-H318-H350

[ 警示性声明 ]:
P201-P280-P305 + P351 + P338-P308 + P313

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T: Toxic;

[ 风险声明 (欧洲) ]:
R45

[ 安全声明 (欧洲) ]:
S53-S45

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
CB0540000

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分散蓝1下游产品

分散蓝1文献

Multifunctional core-shell nanoparticles: discovery of previously invisible biomarkers.

J. Am. Chem. Soc. 133(47) , 19178-88, (2011)

Many low-abundance biomarkers for early detection of cancer and other diseases are invisible to mass spectrometry because they exist in body fluids in very low concentrations, are masked by high-abund...

Assessment of the sensitizing potential of textile disperse dyes and some of their metabolites by the loose-fit coculture-based sensitization assay (LCSA).

Arch. Toxicol. 86(5) , 733-40, (2012)

Certain textile disperse dyes are known to cause allergic reactions of the human skin. Here, we examined 8 disperse dyes and 7 products of azo-cleavage of these dyes in an in vitro assay. We used the ...

Disperse Blue 1.

IARC Monogr. Eval. Carcinog. Risks Hum. 48 , 139-48, (1990)

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