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4-羟基喹啉-2-甲酸乙酯

4-羟基喹啉-2-甲酸乙酯名称

[ CAS 号 ]:
24782-43-2

[ 中文名 ]:
4-羟基-2-乙基喹啉羧酸酯

[ 英文名 ]:
Ethyl 4-hydroxyquinoline-2-carboxylate

[中文别名 ]:

[英文别名 ]:

Ethyl 4-oxo-1,4-dihydro-2-quinolinecarboxylate
Ethyl 4-hydroxyquinoline-2-carboxylate
ETHYL 4-HYDROXY-2-QUINOLINECARBOXYLATE
Kynurenic acid ethyl ester
MFCD01863732

4-羟基喹啉-2-甲酸乙酯物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
343.7±42.0 °C at 760 mmHg

[ 熔点 ]:
216-218ºC(lit.)

[ 分子式 ]:
C₁₂H₁₁NO₃

[ 分子量 ]:
217.221

[ 闪点 ]:
161.7±27.9 °C

[ 精确质量 ]:
217.073898

[ PSA ]:
59.42000

[ LogP ]:
2.57

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.569

[ 储存条件 ]:
室温，干燥密封

4-羟基喹啉-2-甲酸乙酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933499090

4-羟基喹啉-2-甲酸乙酯合成路线

详细合成路线

4-羟基喹啉-2-甲酸乙酯海关

[ 海关编码 ]: 2933499090

[ 中文概述 ]:
2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-羟基喹啉-2-甲酸乙酯文献

Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2.

Br. J. Pharmacol. 162 , 733-748, (2011)

GPR35 is a poorly characterized G protein-coupled receptor at which kynurenic acid has been suggested to be the endogenous ligand. We wished to test this and develop assays appropriate for the study o...

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